Abstract
Two plaque mutants 1a and 2c of the mouse hepatitis virus JHM strain (MHV-JHM) from persistently infected DBT cells2 were examined for neuropathogenicity in mice. The mutant strains had peplomer proteins different from those of the original MHV-JHM3 and they were plaque purified.
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N. Goto, M. Takaoka, N. Hirano, K. Takahashi and K. Fujiwara, Neuro-pathogenicity of a mutant mouse hepatitis virus, JHM strain, derived from persistently infected DBT cells. Jpn. J. Vet. Sci. 46, 459–465. (1984).
N. Hirano, N. Goto, S. Makino and K. Fujiwara, Persistent infection with mouse hepatitis virus JHM strain in DBT cell culture. pp. 301–308. In V. ter Meulen, S. Siddell and H. Wege (eds), Biochemistry and biology of coronaviruses, Pleunum Publishing Corporation, New York. (1981).
S. Makino, F. Taguchi, M. Hayami and K. Fujiwara, Characterization of small plaque mutant of mouse hepatitis virus, JHM strain. Microbiol. Immunol. 27, 445–454. (1983).
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© 1987 Plenum Press, New York
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Goto, N., Makino, S., Fujiwara, K. (1987). Neuropathogenicity of Mutant Strains of Mouse Hepatitis Virus, 1a and 2c, from DBT Cells Persistently Infected with JHM Strain. In: Lai, M.M.C., Stohlman, S.A. (eds) Coronaviruses. Advances in Experimental Medicine and Biology, vol 218. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1280-2_53
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DOI: https://doi.org/10.1007/978-1-4684-1280-2_53
Publisher Name: Springer, Boston, MA
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