Abstract
Coronaviruses display a characteristic fringe of large (17–20 nm), clubshaped peplomers, each consisting of a di- or trimer of the peplomer protein (Cavanagh et al. 1983). The peplomer protein, E2, plays an important role during the infection proces. It mediates the binding of virions to the host-cell receptors and is involved in membrane fusion. In addition, the E2 protein appears to be a major inducer of protective immunity to coronaviral infection (reviewed by Sturman and Holmes, 1983).
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Keywords
- Infectious Bronchitis Virus
- Coiled Coil
- Heptad Repeat
- Mouse Hepatitis Virus
- Infectious Bronchitis Virus Strain
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© 1987 Plenum Press, New York
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de Groot, R.J. et al. (1987). Sequence and Structure of the Coronavirus Peplomer Protein. In: Lai, M.M.C., Stohlman, S.A. (eds) Coronaviruses. Advances in Experimental Medicine and Biology, vol 218. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1280-2_4
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DOI: https://doi.org/10.1007/978-1-4684-1280-2_4
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