Abstract
Interaction of a membrane receptor with its ligand results in the generation of second messengers which ultimately leads to alteration in cell function either by changes in nuclear transcription, or activation/inactivation of cellular enzymes by phosphorylation events. Although the cell-surface MHV receptor has been cloned and sequenced1, the biochemical events leading to the expression of MHV-3 induced PCA after the binding of the virus to its receptor are unknown.
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References
Dveksler, G., Pensiero, M., Cardellichio, C. et al. J. Virol. 65,6881, 1991.
Lyberg, T., Prydz, H. J. Biochem. 194,699, 1981.
Prydz, H., Lyberg, T. Biochem. Pharmacol. 29,9, 1980.
Bach, F., Ifkin, D. Proc. Natl. Acad. Sci. USA. 87,6995. 1990.
Kucey, D., Cheung, P., Rotstein, O. Infect Immun. In press, 1992.
Abecassis, M., Falk, J., Makowka, L. et. al. J. Clin. Invest. 80,881, 1987.
Edgington, T., Pizzalato, M. Thromb. Haemostasis. 50,148, 1983.
Goodwin, J., Bromberg, S., Mesner, R. Cell. Immunol. 60,298, 1981.
Novogrodsky, A., Patya, A., Rubin, A., Stenzel, K. Biochem. Biophys. Res. Comm. 114,93, 1983.
Laurenza, A., Khandelwal, Y., De Souza, N. et al. Mol. Pharmacol. 32,133 1987.
Downey, G., Elson, E., Schwab, B.,et al. J. Cell. Biol. 114,1179, 1991.
Chung, S., Sinclair, S., Fung, L. et al. Prostaglandins 42,501, 1991.
Sinclair, S., Abecassis, M., Wong, P.Y. et al. Adv. Exp. Med. Biol. 276,533, 1990.
Freissmuth, M., Casey, P., Gilman, A. FASEB J. 3,2126, 1989.
Gilman, A. Ann. Rev. Biochem. 56,615, 1987.
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Chung, S., Downey, G., Rotstein, O., Levy, G. (1994). Early Cellular Events in the Induction of Murine Hepatitis Virus (MHV-3) Induced Macrophage Procoagulant Activity (PCA). In: Laude, H., Vautherot, JF. (eds) Coronaviruses. Advances in Experimental Medicine and Biology, vol 342. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2996-5_59
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DOI: https://doi.org/10.1007/978-1-4615-2996-5_59
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