Abstract
Previous studies have shown that IgE antibody is a cause of hay fever and probably involved in other allergic diseases (1). These findings immediately raised the possibility that prevention or suppression of IgE antibody response may have clinical value for hay fever patients. Our approach to this goal was to establish a cell culture system and adoptive transfer system for the analysis of cellular events in the IgE antibody response, and to study immunological effects of hyposensitization treatment in an animal model. In this presentation, I would like to briefly summarize recent progress in our approaches.
This work was supported by Research grants AI-11202 from U. S. Public Health Service, GB-41443 from National Science Foundation and John A. Hartford Foundation. This is publication #214 from the O’Neill Laboratories at the Good Samaritan Hospital.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ishizaka, T. and Ishizaka, K., Progress in Allergy, 19: 60, 1975.
Ishizaka, K. and Kishimoto, T., J. Immunol., 109: 65, 1972.
Kishimoto, T. and Ishizaka, K., J. Immunol., 109: 612, 1972.
Kishimoto, T. and Ishizaka, K., J. Immunol., 111: 720, 1973.
Kishimoto, T. and Ishizaka, K., J. Immunol., 109: 1163, 1972.
Okudaira, H. and Ishizaka, K., J. Immunol., 113: 563, 1974.
Hamaoka, T., Newburger, P.E., Katz, D.H. and Benacerraf, B., J. Immunol., 113: 958, 1974.
Julius, M.H., Simpson, E. and Herzenberg, L., Eur. J. Immunol., 3: 645, 1973.
Kishimoto, T. and Ishizaka, K., J. Immunol., 111: 1194, 1973.
Dutton, R.W., Falkoff, R., Hirst, J.A., Hoffman, M., Kappler, J.W., Kettman, J.R., Lesley, J.F. and Vann, D., Progress in Immunology, 1: 355, 1971.
Kishimoto, T. and Ishizaka, K., J. Immunol., 114: 1175, 1975.
Kishimoto, T. and Ishizaka, K., J. Immunol., 112 1685, 1974.
King, T.P., and Norman P.S., Biochemistry, 1: 709, 1962.
King, T.P., Norman, P.S. and Tao, N., Immunochemistry, 11: 83, 1974.
Ishizaka, K., Kishimoto, T., Delespesse, G. and King, T.P., J. Immunol., 113: 70, 1974.
Ishizaka, K., Okudaira, H. and King, T.P., J. Immunol., 114: 110, 1975.
Takatsu, K., Ishizaka, K. and King, T.P., J. Immunol., 115: 1469, 1975.
Gershon, R.K., In Contemp. Topics Immunol., ed. M.D. Cooper and N. L. Warner, Vol. 3, p. 1. Plenum Press, New York 1974.
Takatsu, K. and Ishizaka, K., Cellular Immunol., 20: 276, 1975.
Takatsu, K. and Ishizaka, K., J. Immunol., in press.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1976 Plenum Press, New York
About this chapter
Cite this chapter
Ishizaka, K. (1976). Induction and Suppression of IgE Antibody Response. In: Johansson, S.G.O., Strandberg, K., Uvnäs, B. (eds) Molecular and Biological Aspects of the Acute Allergic Reaction. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4304-2_3
Download citation
DOI: https://doi.org/10.1007/978-1-4613-4304-2_3
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-4306-6
Online ISBN: 978-1-4613-4304-2
eBook Packages: Springer Book Archive