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Gastroesophageal Reflux in Newborns and Premature Infants

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Abstract

Gastro-esophageal reflux (GER) is defined as the retrograde passage of gastric contents back into the esophagus where it does not belong. Food and gastric juice may damage the mucosa, interfere with respiratory function and impair nutrition. This phenomenon, which follows a failure of the anti-reflux barrier, is particularly frequent in infancy, a period during which it is considered a near-normal event. Episodes are usually short, occur after feeds and tend to decrease with the passage of time. When GER becomes bothersome, gastro-esophageal reflux disease (GERD) develops.

In this chapter, only GER and GERD in newborns and young infants are addressed. The mechanisms, symptoms, associated conditions, diagnostic procedures and treatment recommendations are summarized.

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Authors and Affiliations

  1. Department of Pediatric Surgery, Hospital Universitario “La Paz”, Paseo de la Castellana, 261, 28046, Madrid, Spain

    Juan A. Tovar MD, PhD, FEBPS, FAAP(Hon)

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  1. Juan A. Tovar MD, PhD, FEBPS, FAAP(Hon)
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Correspondence to Juan A. Tovar MD, PhD, FEBPS, FAAP(Hon) .

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Editors and Affiliations

  1. Division of Child Health, Alder Hey Children’s NHS Foundation Trust, Liverpool, United Kingdom

    Paul D. Losty

  2. University of Pennsylvania , Philadelphia, Pennsylvania, USA

    Alan W. Flake

  3. Childrens Hospital, University of Helsinki, Helsinki, Finland

    Risto J. Rintala

  4. Royal Children’s Hospital, University of Melbourne, Parkville, Victoria, Australia

    John M. Hutson

  5. Department of Surgery, Meiji University of Integrative Medicine, Kyoto, Japan

    Naomi lwai

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Tovar, J.A. (2018). Gastroesophageal Reflux in Newborns and Premature Infants. In: Losty, P., Flake, A., Rintala, R., Hutson, J., lwai, N. (eds) Rickham's Neonatal Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-4721-3_25

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