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Growth Factors, Oncogenes and Tumour Suppressor Genes

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Book cover Assessment of Cell Proliferation in Clinical Practice

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Abstract

Control of cell proliferation involves a complex interplay between direct mechanisms linking a cell with adjacent cells and their interstitial stroma, and indirect mechanisms mediated through factors carried by organ vasculature. Disruption of the functional integrity of growth regulatory systems may lead to uncontrolled proliferation and abnormal cellular behaviour manifest in a most extreme form in the development of malignant tumours.

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Authors
  1. D. P. Hollywood
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  2. N. R. Lemoine
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Editor information

Editors and Affiliations

  1. Department of Histopathology, UMDS, St Thomas’ Hospital, London, SE1 7EH, UK

    Peter A. Hall BSc, MD, MRCPath (Professor of Histopathology) (Professor of Histopathology)

  2. Department of Histopathology, UMDS, Guy’s Hospital, London, SE1 9RT, UK

    David A. Levison MD, FRCPath (Professor of Histopathology) (Professor of Histopathology)

  3. Imperial Cancer Research Fund, Lincoln’s Inn Fields, London, WC2A 3PN, UK

    Nicholas A. Wright MA, MD, PhD, DSc, FRCPath (Director of Clinical Research, Professor and Director) (Director of Clinical Research, Professor and Director)

  4. Department of Histopathology, Royal Postgraduate Medical School, Hammersmith Hospital, London, W12 0NN, UK

    Nicholas A. Wright MA, MD, PhD, DSc, FRCPath (Director of Clinical Research, Professor and Director) (Director of Clinical Research, Professor and Director)

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© 1992 Springer-Verlag London

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Hollywood, D.P., Lemoine, N.R. (1992). Growth Factors, Oncogenes and Tumour Suppressor Genes. In: Hall, P.A., Levison, D.A., Wright, N.A. (eds) Assessment of Cell Proliferation in Clinical Practice. Springer, London. https://doi.org/10.1007/978-1-4471-3190-8_2

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  • DOI: https://doi.org/10.1007/978-1-4471-3190-8_2

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3192-2

  • Online ISBN: 978-1-4471-3190-8

  • eBook Packages: Springer Book Archive

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