Abstract
Osteopathic manual therapy (OMT) may reduce hyperinflation in patients with chronic obstructive pulmonary disease (COPD) by improving breathing mechanics. The aim of the study was to evaluate the immediate effects of OMT on hyperinflation in stable COPD patients with forced expired volume in 1 s (FEV1) <50% predicted. Nineteen COPD patients of the median age 68 (IQR 63–72) years and the median FEV1 39.8 (IQR 33.4–46.6) % predicted were enrolled into the study. For the first session, patients were randomly assigned to either OMT or sham therapy. During the second session, the two groups of patients were crossed over. Pulmonary function and dyspnea were compared before and after both procedures. Neither pulmonary function nor dyspnea differed significantly before and after OMT or sham procedures. However, 36.7% and 47.4% patients achieved the minimally important difference for residual volume (RV) reduction after both OMT and sham therapy, respectively. Responders to OMT had a greater median (IQR) baseline sense of dyspnea compared to non-responders, assessed on a visual analog scale, of 7.0 (4.5–7.0) vs. 3.0 (0.0–5.0), p = 0.040, respectively. Although OMT did not have an immediate effect on hyperinflation or dyspnea, a subgroup experienced a reduction in RV following OMT and sham therapy. Future studies are needed to identify the characteristics of responders.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Bolton CE, Bevan–Smith EF, Blakey JD et al (2013) British Thoracic Society Pulmonary Rehabilitation Guideline Development Group; British Thoracic Society Standards of Care Committee. British Thoracic Society guideline on pulmonary rehabilitation in adults. Thorax 68:ii1–i30
Bougie JD, Morgenthal AP (2001) The aging body: conservative management of common neuromusculoskeletal conditions. McGraw Hill Medical, New York
Celli BR (2017) Pulmonary rehabilitation. Up–to–Date. https://www.uptodate.com/contents/pulmonary–rehabilitation. Accessed 23 on Feb 2018
Cicchitti L, Martelli M, Cerritelli F (2015) Chronic inflammatory disease and osteopathy: a systematic review. PLoS One 10(3):e0121327
Cruz–Montecinos C, Godoy–Olave D, Contreras–Briceño FA, Gutiérrez P, Torres–Castro R, Miret–Venegas L, Engel RM (2017) The immediate effect of soft tissue manual therapy intervention on lung function in severe chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 12:691–696
Engel RM, Vemulpad SR (2008) Immediate effects of osteopathic manipulative treatment in elderly patients with chronic obstructive pulmonary disease. J Am Osteopath Assoc 108(10):541–542
Engel RM, Vemulpad SR, Beath K (2013) Short–term effects of a course of manual therapy and exercise in people with moderate chronic obstructive pulmonary disease: a preliminary clinical trial. J Manip Physiol Ther 36(8):490–496
Engel RM, Gonski P, Beath K, Vemulpad S (2016) Medium term effects of including manual therapy in a pulmonary rehabilitation program for chronic obstructive pulmonary disease (COPD): a randomized controlled pilot trial. J Man Manip Ther 24(2):80–89
GOLD (2016) Global initiative for chronic obstructive lung disease. Global strategy for the diagnosis, management and prevention of COPD. https://www.goldcopd.org/global–strategy–diagnosis–management–prevention–copd–2016. Accessed on 30 Jan 2018
GOLD (2019) Global initiative for chronic obstructive lung disease. Global strategy for the diagnosis, management and prevention of COPD. http://www.goldcopd.org. Accessed on 18 Mar 2019
Hartman JE, Ten Hacken NH, Klooster K, Boezen HM, de Greef MH, Slebos DJ (2012) The minimal important difference for residual volume in patients with severe emphysema. Eur Respir J 40:1137–1141
Heneghan NR, Adab P, Balanos GM, Jordan RE (2012) Manual therapy for chronic obstructive airways disease: a systematic review of current evidence. Man Ther 17:507–518
Hogg L, Garrod R, Thornton H, McDonnell L, Bellas H, White P (2012) Effectiveness, attendance, and completion of an integrated, system–wide pulmonary rehabilitation service for COPD: prospective observational study. COPD 9:546–554
Howell RK, Allen TW, Kappler RE (1975) The influence of osteopathic manipulative therapy in the management of patients with chronic obstructive pulmonary disease. J Am Osteopath Assoc 74:757–760
Jones PW, Harding G, Berry P, Wiklund I, Chen WH, Kline Leidy N (2009) Development and first validation of the COPD assessment test. Eur Respir J 34:648–654
Langer D, Ciavaglia CE, Neder JA, Webb KA, O’Donnell DE (2014) Lung hyperinflation in chronic obstructive pulmonary disease: mechanisms, clinical implications and treatment. Expert Rev Respir Med 8:731–749
Marx G, Nasse M, Stanze H, Boakye SO, Nauck F, Schneider F (2016) Meaning of living with severe chronic obstructive lung disease: a qualitative study. BMJ Open 6(12):e011555
Meshe OF, Claydon LS, Bungay H, Andrew S (2017) The relationship between physical activity and health status in patients with chronic obstructive pulmonary disease following pulmonary rehabilitation. Disabil Rehabil 39:746–756
Miller MR, Hankinson J, Brusasco V et al (2005) ATS/ERS task force. Standardisation of spirometry. Eur Respir J 26:319–338
Morais N, Cruz J, Marques A (2016) Posture and mobility of the upper body quadrant and pulmonary function in COPD: an exploratory study. Braz J Phys Ther 20:345–354
Noll DR, Degenhardt BF, Johnson JC, Burt SA (2008) Immediate effects of osteopathic manipulative treatment in elderly patients with chronic obstructive pulmonary disease. J Am Osteopath Assoc 108:251–257
Pellegrino R, Viegi G, Brusasco V, Crapo RO, Burgos F, Casaburi R, Coates A, van der Grinten CP, Gustafsson P, Hankinson J, Jensen R, Johnson DC, MacIntyre N, McKay R, Miller MR, Navajas D, Pedersen OF, Wanger J (2005) Interpretative strategies for lung function tests. Eur Respir J 26:948–968
Steel A, Sundberg T, Reid R, Ward L, Bishop FL, Leach M, Cramer H, Wardle J, Adams J (2017) Osteopathic manipulative treatment: a systematic review and critical appraisal of comparative effectiveness and health economics research. Musculoskelet Sci Pract 27:165–175
Wanger J, Clausen JL, Coates A, Pedersen OF, Brusasco V, Burgos F, Casaburi R, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Hankinson J, Jensen R, Johnson D, Macintyre N, McKay R, Miller MR, Navajas D, Pellegrino R, Viegi G (2005) ATS/ERS task force. Standardisation of the measurement of lung volumes. Eur Respir J 26:511–522
Yilmaz Yelvar GD, Cirak Y, Demir Y, Dalikilinc M, Bozkurt B (2016) Immediate effect of manual therapy on respiratory functions and inspiratory muscle strength in patients with COPD. Int J Chron Obstruct Pulmon Dis 11:1353–1357
Zanotti E, Berardinelli P, Bizzarri C, Civardi A, Manstretta A, Rossetti S, Fracchia C (2012) Osteopathic manipulative treatment effectiveness in severe chronic obstructive pulmonary disease: a pilot study. Complement Ther Med 20:16–22
Conflicts of Interest
The authors declare no conflicts of interest in relation to this article.
Ethical Approval
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The project was approved by the institutional Bioethics Committee of the Medical University of Warsaw in Poland and it was registered at ClinicalTrial.gov (NCT02755363).
Informed Consent
Written informed consent was obtained from all individual participants included in the study.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Maskey-Warzechowska, M., Mierzejewski, M., Gorska, K., Golowicz, R., Jesien, L., Krenke, R. (2019). Effects of Osteopathic Manual Therapy on Hyperinflation in Patients with Chronic Obstructive Pulmonary Disease: A Randomized Cross-Over Study. In: Pokorski, M. (eds) Pulmonology. Advances in Experimental Medicine and Biology(), vol 1222. Springer, Cham. https://doi.org/10.1007/5584_2019_418
Download citation
DOI: https://doi.org/10.1007/5584_2019_418
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-34650-8
Online ISBN: 978-3-030-34651-5
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)