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Transport of Iron in Health and Diseases

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Trace Elements in Man and Animals 10

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References

  • Anderson, G.J., Murphy, T.L., Cowley, L., Evans, B.A., Halliday, J.W., and Mclaren, G.D., 1998, Mapping the gene for sex-linked anemia—An inherited defect of intestinal iron absorption in the mouse, Genomics 48, 34–39.

    Article  CAS  Google Scholar 

  • Dix, D.R., Bridgham, J.T., Broderius, M.A., Byersdorfer, C.A., and Eide, D.J., 1994, The FET4 gene encodes the low affinity Fe(II) transport protein of Saccharomyces cerevisiae, Journal of Biological Chemistry 269, 26092–26099.

    CAS  PubMed  Google Scholar 

  • Eastham, E.J., Bell, J.I., and Douglas, A.P., 1977, Iron-transport characteristics of vesicles of brush-border and basolateral plasma membrane from the rat enterocyte, Biochemical Journal 164, 289–294.

    Article  CAS  Google Scholar 

  • Eide, D., Broderius, M., Fett, J., and Guerinot, M.L., 1996, A noveliron-regulated metal transporter from plants identified by functional expression in yeast, Proceedings of the National Academy of Sciences USA 93, 5624–5628.

    Article  CAS  Google Scholar 

  • Feder, J.N., Penny, D.M., Irrinki, A., Lee, V.K., Lebron, J.A., Watson, N., Tsuchihashi, Z., Sigal, E., Bjorkman, P.J., and Schatzman, R.C., 1998, The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding, Proceedings of the National Academy of Sciences USA 95, 1472–1477.

    Article  CAS  Google Scholar 

  • Fleming, M.D., Trenor, C.C., Su, M.A., Foernzler, D., Beier, D.R., Dietrich, W.F., and Andrews, N.C., 1997, Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene, Nature Genetics 16, 383–386.

    Article  CAS  Google Scholar 

  • Green, R., Charlton, R., Seftel, H., Bothwell, T., Mayet, K, Adams, B., Finch, C., and Layrisse, M., 1968, Body iron excretion in man: a collaborative study, American Journal of Medicine 45, 336–353.

    Article  CAS  Google Scholar 

  • Gunshin, H., Mackenzie, B., Berger, U.V., Gunshin, Y., Romero, M.F., Boron, W.F., Nussberger, S., Gollan, J.L., and Hediger, M.A., 1997, Cloning and characterization of a mammalian proton-coupled metalion transporter, Nature 388, 182–188.

    Article  Google Scholar 

  • Iancu, T.C., Shiloh, H., Raja, K.B., Simpson, R.J., Peters, T.J., Perl, D.P., Hsu, A., and Good, P.F., 1995, The hypotransferrinaemic mouse: ultrastructural and laser microprobe analysis observations, Journal of Pathology 177, 83–94.

    Article  CAS  Google Scholar 

  • Kammler, M., Schon, C., and Hantke, K., 1993, Characterization of the ferrous iron uptake system of Escherichia coli, Journal of Bacteriology 175, 6212–6219.

    Article  CAS  Google Scholar 

  • Stearman, R., Yuan, D.S., Yamaguchi-Iwai, Y., Klausner, R.D., and Dancis, A., 1996, A permease-oxidase complex involved in high-affinity iron uptake in yeast, Science 271, 1552–1557.

    Article  CAS  Google Scholar 

  • Supek, F., Supekova, L., Nelson, H., and Nelson, N, 1996, A yeast manganese transporter related to the macrophage protein involved in conferring resistance to mycobacteria, Proce Natl. Acad. Sci. USA 93, 5105–5110.

    Article  CAS  Google Scholar 

  • Wardrop, S.L. and Richardson, D.R., 1999, The effect of intracellular iron concentration and nitrogen monoxide on Nramp2 expression and non-transferrin-bound iron uptake, Eur. J. Biochem. 263, 41–49.

    Article  CAS  Google Scholar 

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© 2002 Kluwer Academic Publishers

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Rolfs, A., Hediger, M.A. (2002). Transport of Iron in Health and Diseases. In: Roussel, A.M., Anderson, R.A., Favier, A.E. (eds) Trace Elements in Man and Animals 10. Springer, New York, NY. https://doi.org/10.1007/0-306-47466-2_256

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  • DOI: https://doi.org/10.1007/0-306-47466-2_256

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-306-46378-5

  • Online ISBN: 978-0-306-47466-8

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