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Integrative Aspects of Zinc Metabolism and Function

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References

  • Barila, D., Murgia, C., Nobili, F., Gaetani, S., and Perozzi, G., 1994, Subtractive hybridization cloning of novel genes differentially expressed during intestinal development, Eur. J. Biochem. 223:701–709.

    Article  CAS  Google Scholar 

  • Blanchard, R.K. and Cousins, R.J., 1996, Differential display of intestinal mRNAs regulated by dietary zinc, Proc Natl. Acad. Sci. USA 93:6863–6868.

    Article  CAS  Google Scholar 

  • Blanchard, R.K. and Cousins, R.J., 1997, Upregulation of rat intestinal uroguanylin mRNA by dietary zinc restriction, Am. J. Physiol. 272:G972–G978.

    CAS  PubMed  Google Scholar 

  • Cousins, R.J., 1994, Metal elements and gene expression, in: Annual Review of Nutrition (R.E. Olson, ed.), pp. 449–469, Annual Reviews Inc., Palo Alto, CA.

    Google Scholar 

  • Cousins, R.J., 1996, Zinc, in: Present Knowledge in Nutrition, 7th ed. (L.J. Filer and E.E. Ziegler, eds.), pp. 293–306, Internat. Life Sci. Inst.-Nutr. Foundation, Washington.

    Google Scholar 

  • Cousins, R.J., 1997, Differential mRNA display, competitive polymerase chain reaction and transgenic approaches to investigate zinc responsive genes in animals and man, in: Trace Elements in Man and Animals—9: Proceedings of the Ninth International Symposium on Trace Elements in Man and Animals (P.W.F. Fischer, M.R. ’Abbé, K.A. Cockell, and R.S. Gibson, eds.), pp. 649–652, NRC Research Press, Ottawa, Canada.

    Google Scholar 

  • Cousins, R.J., 1998, A role of zinc in the regulation of gene expression, Proc. Nutr. Soc. 57:307–311.

    Article  CAS  Google Scholar 

  • Hallquist, N.A., Khoo, C., and Cousins, R.J., 1996, Lipopolysaccharide regulates cysteine-rich intestinal protein, a zinc-finger protein, in immune cells and plasma, J. Leukoc. Biol. 59:172–177.

    Article  CAS  Google Scholar 

  • Hempe, J.M. and Cousins, R.J., 1991, Cysteine-rich intestinal protein binds zinc during transmucosal zinc transport, Proc. Natl. Acad. Sci. USA 88:9671–9674.

    Article  CAS  Google Scholar 

  • Huang, L. and Gitschier, J., 1997, A novel gene involved in zinc transport is deficient in the lethal milk mouse, Nature Genetics 17:292–297.

    Article  CAS  Google Scholar 

  • Jacob, C., Maret., W., and Vallee, B.L., 1999, Selenium redox biochemistry of zinc-sulfur coordination sites in proteins and enzymes. Proc. Natl. Acad. Sci. USA 96:1910–1914.

    Article  CAS  Google Scholar 

  • Kägi, J.H.R. and Nordberg, M., 1979, Metallothionein, Birkhauser Verlag, Basel, Switzerland.

    Book  Google Scholar 

  • Khoo, C., Blanchard, R.K., Sullivan, V.K., and Cousins, R.J., 1997, Human cysteine-rich intestinal protein: cDNA cloning and expression of recombinant protein and identification in human peripheral blood mononuclear cells, Protein Expression and Purification 9:379–387.

    Article  CAS  Google Scholar 

  • Klug A. and Schwabe, J.W., 1995, Protein motifs 5. Zinc fingers, FASEB J. 9:597–604.

    Article  CAS  Google Scholar 

  • Lanningham-Foster, L., Cottey, R.J., Bender, B.S., and Cousins, R.J., 1999, Overexpression of the zinc-finger protein cysteine-rich intestinal protein (CRIP) in CRIP transgenic mice increases sensitivity to lipopolysaccharide and influenza virus challenge, FASEB J. 13:A872 (abs. 659.5).

    Google Scholar 

  • Lee, D.-Y., Shay, N.F., and Cousins, R.J., 1992, Altered zinc metabolism occurs in murine lethal milk syndrome, J. Nutr. 122:2233–2238.

    Article  CAS  Google Scholar 

  • McMahon, R.J. and Cousins, R.J., 1998a, Mammalian zinc transporters, J. Nutr. 128:667–670.

    Article  CAS  Google Scholar 

  • McMahon, R.J. and Cousins, R.J., 1998b, Regulation of the zinc transporter ZnT-1 by dietary zinc, Proc. Natl. Acad. Sci. USA 95:4841–4846.

    Article  CAS  Google Scholar 

  • Moore, J.B, Blanchard, R.K., and Cousins, R.J., 1999, Identification of dietary zinc regulated expressed sequence tags in murine thymus by mRNA differential display, FASEB J. 13:A241 (abs. 215.4).

    Google Scholar 

  • Palmiter, R.D. and Findley, S.D., 1995, Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc, EMBO J. 14:639–649.

    Article  CAS  Google Scholar 

  • Palmiter, R.D., Cole, T.B., and Findley, S.D., 1996a, ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration, EMBO J. 15:1784–1791.

    Article  CAS  Google Scholar 

  • Palmiter, R.D., Cole, T.B., Quaife, C.J., and Findley, S.D., 1996b, ZnT-3, a putative transporter of zinc into synaptic vesicles, Proc. Natl. Acad. Sci. USA 93:14934–14939.

    Article  CAS  Google Scholar 

  • Pattison, S.E. and Cousins, R.J., 1986, Kinetics of zinc uptake and exchange by primary cultures of rat hepatocytes, Am. J. Physiol. 250:E677–E685.

    CAS  PubMed  Google Scholar 

  • ák,, and Kägi, J.H.R., 1998, Modulation of DNA binding of a Tramtrack zinc finger peptide by the metallothionein-thionein conjugate pair, J. Biol. Chem. 273:17425–17432.

    Article  Google Scholar 

  • Underwood, E.J., 1977, Trace Elements in Human and Animal Nutrition, 4th ed., Academic Press, New York.

    Google Scholar 

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Cousins, R.J. (2002). Integrative Aspects of Zinc Metabolism and Function. In: Roussel, A.M., Anderson, R.A., Favier, A.E. (eds) Trace Elements in Man and Animals 10. Springer, New York, NY. https://doi.org/10.1007/0-306-47466-2_1

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  • DOI: https://doi.org/10.1007/0-306-47466-2_1

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