Molecular Diagnostics

For the Clinical Laboratorian

  • William B. Coleman
  • Gregory J. Tsongalis

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Introduction

    1. Front Matter
      Pages 1-1
  3. Basic Molecular Biology

    1. Front Matter
      Pages 11-11
    2. Paul N. Bogner, Anthony A. Killeen
      Pages 25-30
    3. Terry Amiss, Sharon Collins Presnell
      Pages 31-46
    4. William B. Coleman, Gregory J. Tsongalis
      Pages 47-55
    5. Sharon L. Ricketts
      Pages 57-61
  4. Molecular Diagnostic Technologies

    1. Front Matter
      Pages 63-63
    2. Ian M. Frayling, Emma Monk, Rachel Butler
      Pages 65-74
    3. Deborah A. Payne, Laurie E. Sower
      Pages 75-84
    4. Ulrich Broeckel, Martin J. Hessner
      Pages 111-120
    5. David Neil Hayes, Matthew Meyerson
      Pages 121-148
    6. Alexander Dobrovic
      Pages 149-160
  5. Other Clinical Diagnostic Technologies

    1. Front Matter
      Pages 161-161
    2. Joseph A. DiGiuseppe
      Pages 163-172
    3. Martha B. Keagle
      Pages 173-187
    4. Suneel D. Mundle, Robert J. Koska
      Pages 189-202

About this book


Taking advantage of the many major advances that have occurred since their groundbreaking first edition was published, William B. Coleman and Gregory J. Tsongalis have updated and expanded their highly praised tutorial guide to molecular diagnostic techniques to include not only improved traditional methods, but also totally new molecular technologies, some not yet in routine use. The authors offer cutting-edge molecular diagnostics for genetic disease, human cancers, infectious diseases, and identity testing, as well as new insights into the question of quality assurance in the molecular diagnostics laboratory. Additional chapters address other technologies found in the clinical laboratory that are complementary to molecular diagnostic methodologies, and also discuss genetic counseling and the ethical and social issues involved with nucleic acid testing.

Authoritative and state-of-the-art, Molecular Diagnostics: For the Clinical Laboratorian, 2nd Edition is the essential textbook of choice for anyone working in molecular diagnostics and who wants to remain current with this rapidly changing field.


DNA DNA sequencing Laboratory PCR bioinformatics diagnostics gene expression genes genetics hybridization infectious diseases polymer virus

Editors and affiliations

  • William B. Coleman
    • 1
  • Gregory J. Tsongalis
    • 2
  1. 1.Department of Pathology and Laboratory MedicineUniversity of North Carolina School of MedicineChapel HillUSA
  2. 2.Department of PathologyDartmouth-Hitchcock Medical CenterLebanonUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2005
  • Publisher Name Humana Press
  • eBook Packages Medicine
  • Print ISBN 978-1-58829-356-5
  • Online ISBN 978-1-59259-928-8
  • About this book
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