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  • Book
  • © 2003

Drugs of Abuse

Neurological Reviews and Protocols

Editors:

  1. John Q. Wang

    1. School of Pharmacy, University of Missouri-Kansas City, Kansas, USA

    View editor publications

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Part of the book series: Methods in Molecular Medicine (MIMM, volume 79)

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Table of contents (35 protocols)

  3. Striatal Culture Preparation

    1. Front Matter

      Pages 377-377
      PDF

    2. Primary Striatal Neuronal Culture

      • Limin Mao, John Q. Wang
      Pages 379-386

    4. Primary Culture of Adult Neural Progenitors

      • Steffany A. L. Bennett, Lysanne Melanson-Drapeau
      Pages 397-404

    5. Organotypic Culture of Developing Striatum

      • Fu-Chin Liu
      Pages 405-412

  4. Detection of Transmitter Release in the Striatum

    1. Front Matter

      Pages 413-413
      PDF

    3. HPLC/EC Detection and Quantification of Acetylcholine in Dialysates

      • James A. Zackheim, Elizabeth D. Abercrombie
      Pages 433-441

    4. Real-Time Measurements of Phasic Changes in Extracellular Dopamine Concentration in Freely Moving Rats by Fast-Scan Cyclic Voltammetry

      • Paul E. M. Phillips, Donita L. Robinson, Garret D. Stuber, Regina M. Carelli, R. Mark Wightman
      Pages 443-464

  5. Behvioral Assessment and Others

    1. Front Matter

      Pages 473-473
      PDF
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About this book

Drugs of Abuse: Neurological Reviews and Protocols is intended to provide insightful reviews of key current topics and, particularly, state-- the-art methods for examining drug actions in their various neuroanato- cal, neurochemical, neurophysiological, neuropharmacological, and molecular perspectives. The book should prove particularly useful to n- comers (graduate students and technicians) in this field, as well as to those established scientists (neuroscientists, biochemists, and molecular biologists) intending to pursue new careers or directions in the study of drugs. The book’s protocols cover a wide variety of coherent methods for gathering inf- mation on quantitative changes in proteins and mRNAs at both tissue and cel- lar levels. Inducible gene expression in striatal neurons has been a hot topic over the last decade. Alterations in gene expression for a wide range of proteins in the striatum have been investigated in response to drug administration. Altered expression of given mRNAs and their product proteins constitutes essential molecular steps in the development of neuroplasticity related to long-term addictive properties of drugs of abuse. With the multiple labeling methods that are also described in the book, gene expression can be detected in a chemically identified cell phenotype; the expression of multiple genes of interest can be detected in a single cell simultaneously. Hundreds or thousands of gene expr- sion products can today be detected in one experimental setup using the pow- ful systematic cDNA macroarray or microarray screening technology. Moreover, protocols useful in analyzing the functional roles of genes and proteins (e. g.
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Reviews

"It describes in detail laboratory methods used by researchers working in the area of drug abuse and drug addiction. This is a unique book. Few books deal in detail with the methods underlying experiments. It will be of primary value to active investigators with active laboratories."-Doody's Health Sciences Book Review Journal
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Editors and Affiliations

  • School of Pharmacy, University of Missouri-Kansas City, Kansas, USA

    John Q. Wang

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Bibliographic Information

  • Book Title: Drugs of Abuse

  • Book Subtitle: Neurological Reviews and Protocols

  • Editors: John Q. Wang

  • Series Title: Methods in Molecular Medicine

  • DOI: https://doi.org/10.1385/1592593585

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2003

  • Hardcover ISBN: 978-1-58829-057-1Published: 11 December 2002

  • Softcover ISBN: 978-1-61737-328-2Published: 09 November 2010

  • eBook ISBN: 978-1-59259-358-3Published: 01 February 2008

  • Series ISSN: 1543-1894

  • Series E-ISSN: 1940-6037

  • Edition Number: 1

  • Number of Pages: XIV, 514

  • Topics: Pharmacy

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Pharma

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Buy it now

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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