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  • © 2001

Meningococcal Vaccines

Methods and Protocols

Part of the book series: Methods in Molecular Medicine (MIMM, volume 66)

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  • ISBN: 978-1-59259-148-0
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Softcover Book USD 149.99
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Table of contents (28 protocols)

  1. Serogroup B and C Serum Bactericidal Assays

    • Ray Borrow, George M. Carlone
    Pages 289-304
  2. Whole-Blood Model

    • Catherine A. Ison
    Pages 317-329
  3. T-Cell Responses Against Meningococcal Antigens

    • Lisbeth Meyer Næss, Fredrik Oftung, Audun Aase, Terje E. Michaelsen, Andrew J. Pollard
    Pages 339-348
  4. CD4 T-Cell Epitope Mapping

    • Alexei A. Delvig, John H. Robinson
    Pages 349-360
  5. Epitope Mapping

    • John E. Heckels, Myron Christodoulides
    Pages 361-370
  6. Meningococcal Vaccine Trials

    • Paddy Farrington, Elizabeth Miller
    Pages 371-393
  7. Back Matter

    Pages 403-421

About this book

The development of a comprehensive vaccine against Neisseria meningitidis, the causative agent of meningococcal disease, has remained elusive because of bacterial diversity and immunologic evasion. In Meningococcal Vaccines: Methods and Protocols, Andrew Pollard and Martin Maiden have assembled an impressive collection of the latest molecular and cellular techniques for the development, evaluation, and implementation of vaccines to be used against this dreaded disease. The contributors-leading scientists, clinicians, and public health physicians-describe in detail the many approaches to vaccine design, as well as the assessment of immune response to vaccine candidates and novel vaccine formulations. They also present as a test case the recent implementation of a new meningococcal vaccine in the United Kingdom. A companion volume, Meningococcal Disease: Methods and Protocols, contains detailed methods for diagnostic microbiology, bacterial characterization, epidemiology, host-pathogen interactions, and clinical studies.
Timely and comprehensive, Meningococcal Vaccines: Methods and Protocols provides the scientist, public health physician, epidemiologist, clinical microbiologist, and clinician with the essential tools to lay bare the secrets of the meningococcus and to develop, evaluate, and implement successful new meningococcal vaccines.

Keywords

  • infectious diseases

Reviews

"This volume is an impressive collection of the latest techniques in the development, evaluation and application of meningococcal vaccines. The easy-to-follow protocols each preceded by a brief introduction into the topic were provided by leading scientists in the field. Andrew Pollard and Martin Maiden did a great job in assembling these protocols into one volume - a work we all in the meningococcal field have waited for." - International Journal of Medical Microbiology.

"The strength of this text is that it provides a key reference source, enabling researchers in the field to avoid reinventing the wheel. The text also provides the basis for the development of new ideas. Each chapter takes a step-by-step approach with clearly set out notes highlighting the problem areas. All the chapters have comprehensive bibliographies, and are well structured. The text is easily accessible and is recommended to those who are seeking to critically appraise the field of meningococcal vaccines." - Epidemiology and Infection

"This book and its accompanying volume are well produced, easy to read and well edited. Andrew Pollard and Martin Maiden are to be congratulated in bringing together in these two volumes an enormous amount of information about this very important topical infection." -Molecular Biotechnology

Editors and Affiliations

  • BC Research Institute for Children’s and Women’s Health, Vancouver, Canada

    Andrew J. Pollard

  • Wellcome Trust Centre for the Epidemiology of Infectious Disease, Oxford, UK

    Martin C.J. Maiden

Bibliographic Information

  • Book Title: Meningococcal Vaccines

  • Book Subtitle: Methods and Protocols

  • Editors: Andrew J. Pollard, Martin C.J. Maiden

  • Series Title: Methods in Molecular Medicine

  • DOI: https://doi.org/10.1385/1592591485

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2001

  • Hardcover ISBN: 978-0-89603-801-1

  • Softcover ISBN: 978-1-4899-4225-8

  • eBook ISBN: 978-1-59259-148-0

  • Series ISSN: 1543-1894

  • Series E-ISSN: 1940-6037

  • Edition Number: 1

  • Number of Pages: XVII, 421

  • Number of Illustrations: 20 b/w illustrations

  • Topics: Diseases

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

Buying options

eBook USD 109.00
Price excludes VAT (USA)
  • ISBN: 978-1-59259-148-0
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 149.99
Price excludes VAT (USA)
Hardcover Book USD 229.00
Price excludes VAT (USA)