Overview
- Editors:
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Yvonne A. Barnett
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School of Biomedical Sciences, University of Ulster, Northern Ireland
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Christopher R. Barnett
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School of Biomedical Sciences, University of Ulster, Northern Ireland
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Table of contents (26 protocols)
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Age-Related Changes to Cellular Biomolecules
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- Jesus R. Requena, David L. Price, Suzanne R. Thorpe, John W. Baynes
Pages 209-217
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Mitochondrial Morphology, Function, and Mutation with Age
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Front Matter
Pages 219-219
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- Jaime Miquel, Carlo Bertoni-Freddari
Pages 221-235
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- Federico V. Pallardo, Juan Sastre, Jaime Miquel, José Viña
Pages 237-244
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- Robert W. Taylor, Theresa M. Wardell, Emma L. Blakely, Gillian M. Borthwick, Elizabeth J. Brierley, Douglass M. Turnbull
Pages 245-264
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- Robert W. Taylor, Richard M. Andrews, Patrick F. Chinnery, Douglass M. Turnbull
Pages 265-277
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Immune System and Aging
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Front Matter
Pages 279-279
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- Beatrix Grubeck-Loebenstein, Maria Saurwein-Teissl, Nikolaus Romani
Pages 291-309
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- Erminia Mariani, Corona Alonso, Rafael Solana
Pages 311-320
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- Derek Middleton, Martin D. Curran, Fionnuala Williams
Pages 321-349
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Case Studies
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Front Matter
Pages 351-351
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Back Matter
Pages 379-385
About this book
Aging is an almost universal process within biological systems, one which leads to a decline in functional capacity, disease onset, and eventually death. There has been much interest in recent years to elucidate the molecular mec- nisms that underlie the aging process. Many theories have been proposed since the last century that aim to explain the causes of aging. There is no one theory that completely satisfies the phenotype of aging, but genetics and environm- tal factors play an important role in the etiology of age-related pathologies and the aging process. However, there is still much to be learned about the aging process which has been termed one of the last great frontiers in biology. De- graphic changes worldwide are leading to increased average life expectancies within our populations. These changes in population characteristics will impact upon the economies of the supporting society, with increasing healthcare and infrastructural costs arising from the prevalence of age-related pathologies and other physical disabilities associated with advancing years. Many researchers worldwide are working in the attempt to identify key cellular processes through which it might one day be possible to slow down the aging process and thus increase the health span of humans. Numerous research projects—from the cellular through to tissue, organ, and whole organism studies—are currently underway to investigate the mul- factorial aging process.
Reviews
"Aging Methods and Protocols brings together a wide variety of molecular experimental techniques for studying the aging process. A group of experts related their own aging experimental methods in a step-by-step manner. This format makes it easy to use and adapt specific techniques for individual laboratories. Aging Methods and Protocols contains a unique group of useful experimental methods. The book is highly recommended for academic research-oriented health science libraries. It is also recommended for individual research laboratories investigating the aging process." - E-STREAMS
