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  • © 1998

Tumor Marker Protocols

Part of the book series: Methods in Molecular Medicine (MIMM, volume 14)

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Table of contents (30 protocols)

  1. Molecular Markers

    1. Front Matter

      Pages 267-267
    2. Applications of Tissue Microdissection in Molecular Pathology

      • Michael R. Emmert-Buck, Irina A. Lubensky, Rodrigo F. Chuaqui, Larisa V. Debelenko, Cathy D. Vocke, Maria J. Merino et al.
      Pages 269-298
    3. p53 Detection in Breast Cancer

      • Penelope L. Davis, J. Dirk lglehart
      Pages 319-330
    4. Detection of Prostate-Cancer Cells in Blood and Bone Marrow by RT-PCR

      • Robert L. Vessella, Eva Corey
      Pages 357-371
    5. Quantitative, Competitive RT-PCR Analysis of Biomarkers in the Study of Neoplasia

      • Richard D. Hockett Jr., Miriam D. Rogers, Sudhir Srivastava
      Pages 373-389
    6. Differential Display to Define Molecular Markers and Genes That Mediate Malignancy

      • Edward J. Pavlik, Katherine Nelson, Suseela Srinivasan, Thomas L. Johnson, Paul D. De Priest
      Pages 391-414
  2. Miscellaneous Markers and Early Detection of Cancer

    1. Front Matter

      Pages 415-415
    2. Transforming Growth Factor Beta

      • Feng-Ming Kong, Mitchell S. Anscher, Randy L. Jirtle
      Pages 417-430
    3. Anti-HMdU Autoantibodies in Human Sera as a Biomarker of Cancer Risk

      • Krystyna Frenkel, Jerzy Karkoszka
      Pages 431-446
    4. A Scientific Basis for Cancer Prevention

      • Sanjay K. Srivastawa, Sanjay Awasthi
      Pages 447-464
    5. d-Glucaric Acid as a Prospective Tumor Marker

      • Zbigniew Walaszek, Maragaret Hanausek, Janusz Szemraj, Alan K. Adams
      Pages 487-495
  3. Back Matter

    Pages 497-500

About this book

The development of cancer is a slow process and it very often takes a number of years before a tumor becomes clinically evident. No current te- nique is sensitive and specific enough to detect tumors at their earliest stage, i. e. , when the tumor is smaller than one billion cells. Consequently, the d- ease is usually diagnosed in an advanced state, very often when it is already beyond the reach of therapeutic strategies. This is the main stumbling block to the secondary prevention that would reduce cancer mortality. There is hope, however, because in the last decade we have witnessed an explosion of reports dealing with tumor markers. In many instances, simple, noninvasive diagnostic tests are becoming available to detect the early signs ofneoplasia. Interest in early detection of neoplasia is growing among those basic scientists, cli- cians, and health professionals who realize that progress in reducing cancer mortality is dependent to a great degree on its early detection and prevention. Some disappointment usually accompanies these discoveries, because what at first glance proves to be promising, is in many instances, applicable only to a limited number of cases. What is the cause of these failures? The answer may be that cancer is a multitude of neoplastic diseases in which endogenous and exogenous etiologic factors contribute either sim- taneously or over a lifetime to the development of disease.

Editors and Affiliations

  • AMC Cancer Research Center, Denver

    Margaret Hanausek, Zbigniew Walaszek

Bibliographic Information

  • Book Title: Tumor Marker Protocols

  • Editors: Margaret Hanausek, Zbigniew Walaszek

  • Series Title: Methods in Molecular Medicine

  • DOI: https://doi.org/10.1385/0896033805

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 1998

  • Hardcover ISBN: 978-0-89603-380-1Published: 09 March 1998

  • Softcover ISBN: 978-1-61737-019-9Published: 09 November 2010

  • eBook ISBN: 978-1-59259-598-3Published: 01 February 2008

  • Series ISSN: 1543-1894

  • Series E-ISSN: 1940-6037

  • Edition Number: 1

  • Number of Pages: XIV, 500

  • Topics: Pathology

  • Industry Sectors: Biotechnology, Finance, Business & Banking, Health & Hospitals, Pharma

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access