Cell-Cell Interactions

Methods and Protocols

  • Sean P. Colgan

Part of the Methods in Molecular Biology™ book series (MIMB, volume 341)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Michael Aschner, Vanessa A. Fitsanakis, Ana Paula Marreilha dos Santos, Luisa Olivi, Joseph P. Bressler
    Pages 1-15
  3. Nancy A. Louis, Dionne Daniels, Sean P. Colgan
    Pages 51-59
  4. Holger K. Eltzschig, Thomas Weissmüller, Alice Mager, Tobias Eckle
    Pages 73-87
  5. Genevieve B. Wortzman, Allison J. Gardner, Janice P. Evans
    Pages 89-101
  6. Peter Ngo, Punitha Ramalingam, Jonathan A. Phillips, Glenn T. Furuta
    Pages 103-109
  7. Juan C. Ibla, Joseph Khoury
    Pages 111-117
  8. Michelle L. Matter, Joe W. Ramos
    Pages 155-165
  9. Anita J. Merritt, Anthea Scothern, Tanusree Bhattacharyya
    Pages 167-183
  10. Markus Utech, Matthias Brüwer, Asma Nusrat
    Pages 185-195
  11. Winston Y. Lee, Alex C. Chin, Susan Voss, Charles A. Parkos
    Pages 205-215
  12. Aimee Landry, Ramnik Xavier
    Pages 251-281
  13. Back Matter
    Pages 283-286

About this book


The use of directed cell models to study the manner in which two or more cells interact has revolutionized our understanding of protein-protein interactions in a complex milieu and has provided an invaluable platform for the identification of new molecules. In Cell-Cell Interactions: Methods and Protocols, highly skilled experts in the development and utilization of cell-cell interaction assays describe in detail their best methods-based approaches, both in vitro and in vivo, for uncovering cellular interactions at the molecular level. The protocols cover a diverse set of cell-cell interaction models in both normal and pathological states, are readily adaptable to nearly any cell type and organ system, and include primary data and outcome analysis. In addition, the protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Insightful to beginners and inspiring to seasoned professionals, Cell-Cell Interactions: Methods and Protocols provides the cutting-edge and versatile laboratory tools needed to gain a basic understanding of cell-cell interactions.


bacteria biology biosynthesis cell cloning membrane metabolism microscopy migration molecular biology protein tissue

Editors and affiliations

  • Sean P. Colgan
    • 1
    • 2
  1. 1.Center for Experimental Therapeutics and Reperfusion InjuryBrigham
  2. 2.Women’s Hospital, Havard Medical SchoolBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2006
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-523-1
  • Online ISBN 978-1-59745-113-0
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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