© 2005

Inflammatory Disorders of the Nervous System

Pathogenesis, Immunology, and Clinical Management

  • Alireza Minagar
  • J. Steven Alexander

Part of the Current Clinical Neurology book series (CCNEU)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. J. Steven Alexander, Alireza Minagar
    Pages 1-16
  3. Monica J. Carson, Crystal S. Anglen, Corinne Ploix
    Pages 17-40
  4. Tammy Kielian, Paul D. Drew
    Pages 41-80
  5. William J. Karpus
    Pages 81-90
  6. Wenche Jy, Lawrence L. Horstman, Joaquin J. Jimenez, Alireza Minagar, Yeon S. Ahn
    Pages 91-102
  7. William A. Sheremata
    Pages 103-131
  8. Fabrizio Giuliani, Rana Zabad, V. Wee Yong
    Pages 133-145
  9. Sean J. Pittock, Dean M. Wingerchuk
    Pages 147-162
  10. Dean M. Wingerchuk
    Pages 203-215
  11. Chitra Krishnan, Adam I. Kaplin, Deepa M. Deshpande, Carlos A. Pardo, Douglas A. Kerr
    Pages 217-236
  12. Robert Zivadinov, Rohit Bakshi
    Pages 237-256
  13. Shariq Mumtaz, Marjorie R. Fowler, Eduardo Gonzales-Toledo, Roger E. Kelley
    Pages 257-268
  14. Dakshinamurty Gullapalli, Lawrence H. Phillips II
    Pages 269-290
  15. Deborah Aleman-Hoey, Robin L. Brey
    Pages 291-304
  16. Paul Shapshak, Alireza Minagar, Elda M. Duran, Fabiana Ziegler, Wade Davis, Raman Seth et al.
    Pages 305-318
  17. Michael D. Lairmore, Bindhu Michael, Lee Silverman, Amrithraj Nair
    Pages 319-336
  18. Douglas J. Lanska
    Pages 337-348
  19. Back Matter
    Pages 349-362

About this book


Now well recognized, the critical role of the inflammatory response in the pathophysiology of peripheral and central neurological disorders, including Alzheimer's and Parkinson's diseases, is today the subject of intense investigation at the molecular level. In Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management, a panel of influential basic scientists review in detail the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, CNS vasculitis, neuropsychiatric systemic lupus erythematosis, Alzheimer's disease, and Parkinson's disease. The role of the immune system in neuroinflammation is also explored in such disorders as neurosarcoidosis, HIV-associated dementia, and HTLV-associated neurological disorders.
Cutting-edge and authoritative, Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management offers basic research and clinical scientists an illuminating introduction to the new world of inflammatory CNS conditions and the emerging diagnostic and therapeutic opportunities they provide.


Alzheimer Chemokine Nervous System Parkinson interferon

Editors and affiliations

  • Alireza Minagar
    • 1
  • J. Steven Alexander
    • 1
  1. 1.Louisiana State University Health Science CenterShreveport

Bibliographic information

  • Book Title Inflammatory Disorders of the Nervous System
  • Book Subtitle Pathogenesis, Immunology, and Clinical Management
  • Editors Alireza Minagar
    J. Steven Alezander
  • Series Title Current Clinical Neurology
  • DOI
  • Copyright Information Humana Press Inc. 2005
  • Publisher Name Humana Press
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-58829-424-1
  • Softcover ISBN 978-1-61737-560-6
  • eBook ISBN 978-1-59259-905-9
  • Edition Number 1
  • Number of Pages XIV, 362
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Neurology
  • Buy this book on publisher's site
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From the reviews:

"The objective of this book is to provide the readers with a highly detailed review of the basic principles of neuroinflammation and extensive updates of the latest findings on common neuroinflammatory disorders. … The treatment principles of the different inflammatory disorders are very well covered and up-to-date. This book can be of interest for the institutional library in order for doctors to look up specific details and treatment principles, and to enter deeply into neuroimmunological basics." (Orvar Eeg-Olofsson, European Journal of Paediatric Neurology, Vol. 11, June, 2007)