DNA Vaccines

Methods and Protocols

  • Douglas B. Lowrie
  • Robert G. Whalen

Part of the Methods in Molecular Medicine™ book series (MIMM, volume 29)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Anthony P. Green
    Pages 1-9
  3. Joachim Schorr, Peter Moritz, Martin Schleef
    Pages 11-21
  4. Nancy L. Shen, Jukka Hartikka, Nancy A. Horn, Marston Manthorpe, Magda Marquet
    Pages 23-34
  5. Derek Gregory, Ricardo E. Tascon, Douglas B. Lowrie
    Pages 35-36
  6. Thomas Tüting, Jonathan Austyn, Walter J. Storkus, Louis D. Falo Jr.
    Pages 37-64
  7. Sylvia van Drunen Littel-van den Hurk, Ralph P. Braun, Lorne A. Babiuk
    Pages 79-94
  8. Cynthia L. Brazolot Millan, Heather L. Davis
    Pages 95-98
  9. Joël Heppell, Heather L. Davis
    Pages 99-103
  10. Eric D. Anderson, Jo-Ann C. Leong
    Pages 105-121
  11. Antonio Rosato, Gabriella Milan, Annalisa Zambon, Paola Zanovello, Dino Collavo
    Pages 123-132
  12. John H. Van Uden, Eyal Raz
    Pages 145-168
  13. Risini Weeratna, Arthur M. Krieg, Heather L. Davis
    Pages 169-172
  14. Charles F. Reich, David S. Pisetsky
    Pages 173-184
  15. Jon Norman, Jukka Hartikka, Pamela Strauch, Marston Manthorpe
    Pages 185-196
  16. Kenji Okuda, Susumu Kawamoto, Jun Fukushima
    Pages 197-204
  17. Jong J. Kim, David B. Weiner
    Pages 205-220

About this book


In DNA Vaccines: Methods and Protocols, state-of-the-art review articles by leading experts summarize how to develop and employ the highly promising new DNA vaccines, what clinical results can be expected from their use, and what is known about how they work. Key topics range from vaccine design and construction to preparation and delivery methods, including the use of classical adjuvants, "genetic adjuvants," and the immunostimulatory properties of DNA and selected oligonucleotide sequences. Several contributors provide strategic ideas on antigen engineering and describe the particularly novel applications of DNA vaccine methodology that have recently emerged. In addition, there is a discussion of dendritic cells and antigen-presenting cells, the understanding of whose actions holds great promise for modulating the immune response, and thus for treating disease. Cutting-edge and comprehensive, DNA Vaccines: Methods and Protocols provides a broad panorama of the methods and thinking from which the vaccines of tomorrow will evolve, and so constitutes an invaluable sourcebook for both experts developing new applications and newcomers who want to gain mastery of the techniques and problems involved.

Editors and affiliations

  • Douglas B. Lowrie
    • 1
  • Robert G. Whalen
    • 2
  1. 1.Mycobacterial Research LaboratoryLondonUK
  2. 2.Maxygen Inc.Redwood City

Bibliographic information

  • DOI https://doi.org/10.1385/1592596886
  • Copyright Information Humana Press 2000
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-580-5
  • Online ISBN 978-1-59259-688-1
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • About this book
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