© 2004

Hepatitis B and D Protocols

Volume 1: Detection, Genotypes, and Characterization

  • Robert K. Hamatake
  • Johnson Y. N. Lau

Part of the Methods in Molecular Medicine book series (MIMM, volume 95)

Table of contents

  1. Front Matter
    Pages i-xxiv
  2. Detection of Viral Markers

    1. Front Matter
      Pages 1-1
    2. Stefan Zeuzemro
      Pages 3-13
    3. Wei Zhang, Hans Jörg Hacker, Maria Mildenberger, Qin Su, Claus H. Schröder
      Pages 29-40
    4. Scott Bowden, Kathy Jackson, Margaret Littlejohn, Stephen Locarnini
      Pages 41-50
    5. Jane W. S. Fang, Johnson Y. N. Lau
      Pages 65-69
    6. Antonina Smedile, Maria Grazia Niro, Mario Rizzetto
      Pages 85-93
    7. Thomas B. Macnaughton, Michael M. C. Lai
      Pages 99-105
    8. Karim Abid, Francesco Negro
      Pages 107-111
  3. Viral Genotypes and Variants

About this book


Despite the availability of an effective vaccine, there are still 400 million people worldwide who are chronically infected with the hepatitis B and D viruses (HBV and HDV), and more work still needs to be done in all of the key areas of managing the disease. In Hepatitis B and D Protocols, leading investigators and clinicians have joined forces to create a broad-ranging collection of core techniques for the study of HBV and HDV infections and for the development of therapies to treat them. In this first of two volumes Detection, Genotypes, and Characterization, the authors focus on readily reproducible molecular methods for the identification and quantification of viral markers, the detection and impact of viral variants, and the study of the viral life cycle. Each fully tested protocol is described in step-by-step detail by an established expert in the field and includes a background introduction outlining the principle underlying the technique, equipment and reagent lists, and tips on troubleshooting and avoiding known pitfalls. An accompanying second volume, Immunology, Model Systems, and Clinical Studies, contains user-friendly protocols for the study of host immune responses to infection, in vitro and in vivo models of infection, and the development of antivirals.
Taken together, Hepatitis B and D Protocols, Volume 1: Detection, Genotypes, and Characterization and Volume 2: Immunology, Model Systems, and Clinical Studies offer both new and experienced investigators an encyclopedic collection of powerful tools for studying HBV and HDV infections, as well as an essential resource for finding new therapies to treat chronically infected patients.


Hepatitis antigen infection infections interferon vaccine virus

Editors and affiliations

  • Robert K. Hamatake
    • 1
  • Johnson Y. N. Lau
    • 1
  1. 1.Ribapharm Inc.Costa Mesa

Bibliographic information

  • Book Title Hepatitis B and D Protocols
  • Book Subtitle Volume 1: Detection, Genotypes, and Characterization
  • Editors Robert K. Hamatake
    Johnson Y. N. Lau
  • Series Title Methods in Molecular Medicine
  • DOI
  • Copyright Information Humana Press 2004
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Hardcover ISBN 978-1-58829-105-9
  • eBook ISBN 978-1-59259-669-0
  • Series ISSN 1543-1894
  • Series E-ISSN 1940-6037
  • Edition Number 1
  • Number of Pages , 376
  • Number of Illustrations 109 b/w illustrations, 1 illustrations in colour
  • Topics Infectious Diseases
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Public Health
Internal Medicine & Dermatology


From the reviews:

"Both volumes provide an excellent reference for background information and detailed experimental investigations for both Hepatitis B and Hepatitis D. A major attribute of the volumes is that as they cover a wide range of subjects, the reader has the opportunity to access information they would not normally encounter. Volumes 1 and 2 are an excellent reference source and the methodologies described present the opportunity for both new and experienced researchers to study the molecular aspects of HBV and HDV infection."-SGM Quarterly

" excellent reference for background information and detailed experimental investigations for both Hepatitis B and Hepatitis D...." - Microbiology Today

"The book is an extremely comprehensive collection of valuable modern protocols on detection of HBV DNA in serum and liver … . In summary, the general layout of the book is of excellent quality. Details are painstakingly provided so that sophisticated readers can profit from first hand top quality information derived from people who have personally worked at the bench. The substantial number of references will also allow easy access to the specific literature in the field." (M. Mondelli, Digestive and Liver Disease, Vol. 37, 2005)