Cancer Cytogenetics

Methods and Protocols

  • John Swansbury

Part of the Methods in Molecular Biology™ book series (MIMB, volume 220)

Table of contents

  1. Front Matter
    Pages i-xi
  2. John Swansbury
    Pages 1-8
  3. John Swansbury
    Pages 23-42
  4. John Swansbury
    Pages 59-71
  5. John Swansbury
    Pages 111-123
  6. Pietro Polito, Paola Dal Cin, Maria Debiec-Rychter, Anne Hagemeijer
    Pages 135-150
  7. Toon Min, John Swansbury
    Pages 173-191
  8. Toon Min
    Pages 193-212
  9. Jon C. Strefford
    Pages 235-243
  10. John Swansbury
    Pages 245-257
  11. Back Matter
    Pages 271-283

About this book


Cytogenetic studies of malignancy have become an essential tool in the clinical management of cancer patients, but they are not uniformly utilized, even in well-developed countries. In Cancer Cytogenetics: Methods and Protocols, experienced cytogeneticists describe in step-by-step detail the key cytogenetic and FISH techniques used by modern clinical laboratories in the genetic analysis of human malignancies, as well as explain how best to interpret the results.
The book's practical advice and methods are suitable for use at every level of expertise, including fully established laboratories, but with a sympathetic bias toward anyone considering setting up a new cytogenetics service. Here the reader will find not only elementary tutorials on the fundamentals of human karyotypes and chromosome analysis, but also detailed discussions on how laboratories may optimally upgrade their repertoire of available capabilities to include such newer complementary techniques as CGH, FISH, and M-FISH. Each protocol contains many novel ideas and time-saving techniques, expert commentary, tricks of the trade, alternative approaches, and suggestions that will help yield the results that clinicians want.
Eminently practical for every stage of diagnostic service, Cancer Cytogenetics: Methods and Protocols offers hospital and other pathology laboratories a user-friendly collection of both standard and advanced techniques, all carefully designed to improve the diagnosis and clinical management of cancer patients today.

Editors and affiliations

  • John Swansbury
    • 1
  1. 1.The Royal Marsden NHS TrustThe Institute of Cancer ResearchSuttonUK

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2003
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-080-9
  • Online ISBN 978-1-59259-363-7
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals