Cardiac Cell and Gene Transfer

Principles, Protocols, and Applications

  • Joseph M. Metzger

Part of the Methods in Molecular Biology book series (MIMB, volume 219)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Vectors for Cardiac Gene Transfer

    1. Front Matter
      Pages 1-1
    2. Faris P. Albayya, Joseph M. Metzger
      Pages 3-17
    3. Jeannine M. Scott, Jeffrey S. Chamberlain
      Pages 19-28
    4. Dongsheng Duan, Yongping Yue, John F. Engelhardt
      Pages 29-51
    5. Tsuyoshi Sakoda, Noriyuki Kasahara, Larry Kedes
      Pages 53-70
  3. Cell Transfer to Myocardium

    1. Front Matter
      Pages 71-71
    2. Kevin S. Cahill, Catalin Toma, Mark F. Pittenger, Paul D. Kessler, Barry J. Byrne
      Pages 73-81
    3. Steven M. White, William C. Claycomb
      Pages 83-95
    4. Hans Reinecke, Charles E. Murry
      Pages 97-112
  4. Vectors for Cardiac Gene Transfer

    1. Front Matter
      Pages 113-113
    2. Massimo Buvoli, Ada Buvoli, Leslie A. Leinwand
      Pages 115-127
    3. Leora B. Balsam, Douglas N. Miniati, Robert C. Robbins
      Pages 129-133
    4. Jennifer C. Hirsch, Andrea R. Borton, Joseph M. Metzger
      Pages 145-157
  5. In Vivo Cardiac Gene Transfer

    1. Front Matter
      Pages 167-167
    2. Geir Christensen, Peter J. Gruber, Yibin Wang, Kenneth R. Chien
      Pages 169-178
    3. Federica del Monte, Roger J. Hajjar
      Pages 179-193
    4. Michael L. Szatkowski, Margaret V. Westfall, Joseph M. Metzger
      Pages 195-202
    5. Stephan E. Lehnart, J. Kevin Donahue
      Pages 213-218
    6. Dimitrios Georgakopoulos, David A. Kass
      Pages 233-243
  6. Back Matter
    Pages 245-253

About this book


Cellular and gene-based experimental techniques promise powerful new therapeutic agents for the remediation of both acquired and inherited cardiovascular disease. In Cardiac Cell and Gene Transfer: Principles, Protocols, and Applications, Joseph M. Metzger and a panel of leading scientific experts detail many novel techniques and strategies for the cellular and genetic modification of heart function. These highly experienced authors provide step-by-step protocols for vector production and purification, for gene and cell delivery techniques, and for physiological assessment in vivo and in vitro.
Timely, authoritative, and state-of-the-art, Cardiac Cell and Gene Transfer: Principles, Protocols, and Applications constitutes an invaluable guide to all the new cellular and gene-based technologies needed by basic and clinical investigators working to illuminate today's unanswered questions about heart disease and ultimately to improve the heart performance in all their patients.

Editors and affiliations

  • Joseph M. Metzger
    • 1
    • 2
  1. 1.Department of Physiology, Department of Internal MedicineUniversity of MichiganAnn Arbor
  2. 2.Center for Integrative GenomicsUniversity of MichiganAnn Arbor

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2003
  • Publisher Name Springer, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-994-0
  • Online ISBN 978-1-59259-350-7
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology