© 2002

Malaria Methods and Protocols

Methods and Protocols

  • Denise L. Doolan

Part of the Methods in Molecular Medicine™ book series (MIMM, volume 72)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Assessing Risk of Infection and Severity of Disease

    1. Front Matter
      Pages 1-1
    2. J. Kevin Baird, Michael J. Bangs, Jason D. Maguire, Mazie J. Barcus
      Pages 13-22
  3. Laboratory Models

    1. Front Matter
      Pages 23-23
    2. Robert E. Sinden, Geoff A. Butcher, A. L. Beetsma
      Pages 25-40
    3. Laurent Rénia, Elodie Belnoue, Irène Landau
      Pages 41-55
    4. Latifu A. Sanni, Luis F. Fonseca, Jean Langhorne
      Pages 57-76
    5. William E. Collins
      Pages 77-84
    6. William E. Collins
      Pages 85-92
  4. Diagnosis and Typing

    1. Front Matter
      Pages 93-93
    2. John C. Beier
      Pages 95-101
    3. Georges Snounou
      Pages 103-116
    4. Ingrid Felger, Hans-Peter Beck
      Pages 117-129
    5. Xin-zhuan Su, Michael T. Ferdig
      Pages 131-136
    6. Adam A. Witney, Robert M. Anthony, Daniel J. Carucci
      Pages 137-139
    7. Kyle C. McKenna, Marcelo R. S. Briones
      Pages 141-148
  5. Molecular Biology Techniques

    1. Front Matter
      Pages 149-149

About this book


Despite considerable scientific and medical effort over the past decades, malaria remains the most important human parasitic disease. It is responsible for up to 3 million deaths and another 300-500 million new cases each year, and is becoming resistant to the current chemoprophylactic and chemotherapeutic agents. In Malaria Methods and Protocols, internationally respected scientists and clinicians describe in step-by-step detail their most useful conventional and cutting-edge techniques for the study of malaria. Areas covered include clinical and laboratory diagnosis and typing, animal models, molecular biology, immunology, cell biology, vaccinology, laboratory models, and field applications. Each readily reproducible protocol has been tested, standardized, and optimized for experimental success, and includes many laboratory notes on troubleshooting, avoiding pitfalls, and interpreting results. Several of the most widely used methods are either described here in detail for the first time or have been thoroughly updated since their original publication (e.g., in vitro culture of Plasmodium parasites and in vitro growth inhibition assay).
State-of-the-art and highly practical, Malaria Methods and Protocols makes available to basic and applied researchers today's only comprehensive collection of essential laboratory methods for diagnosing malaria, characterizing the parasite, understanding the interaction between the human host and Plasmodium parasite, and developing effective preventive measures.

Editors and affiliations

  • Denise L. Doolan
    • 1
    • 2
  1. 1.Malaria Program, Naval Medical Research CenterSilver SpringUSA
  2. 2.Department of Molecular Microbiology and ImmunologySchool of Hygiene and Public Health, Johns Hopkins UniversityBaltimoreUSA

Bibliographic information

  • Book Title Malaria Methods and Protocols
  • Book Subtitle Methods and Protocols
  • Editors Denise L. Doolan
  • Series Title Methods in Molecular Medicine™
  • DOI
  • Copyright Information Humana Press 2002
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Hardcover ISBN 978-0-89603-823-3
  • Softcover ISBN 978-1-61737-205-6
  • eBook ISBN 978-1-59259-271-5
  • Series ISSN 1543-1894
  • Series E-ISSN 1940-6037
  • Edition Number 1
  • Number of Pages XV, 631
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Infectious Diseases
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Public Health
Internal Medicine & Dermatology


"In this book, internationally respected scientists and clinicians describe in step-by-step detail their most useful conventional and cutting-edge techniques for the study of malaria." - Clinical Laboratory International

"This is an outstanding collection of protocols written by over eighty experts in the field. The geographical spread of these contributors is impressive, encompassing writers from thirteen countries on six continents. There is good stylistic continuity throughout the book, despite the diversity of the authors...there is admirable cross-referencing between chapters." -Molecular Biotechnology