Integrin Protocols

  • Anthony Howlett

Part of the Methods in Molecular Biology book series (MIMB, volume 129)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Working with Integrins

    1. Front Matter
      Pages 1-1
    2. Erkki Koivunen, Bradley H. Restel, Daniel Rajotte, Johanna Lahdenranta, Martin Hagedorn, Wadih Arap et al.
      Pages 3-17
    3. Marc Delcommenne, Charles H. Streuli
      Pages 19-34
    4. Kishore K. Wary, Michael Dans, Agnese Mariotti, Filippo G. Giancotti
      Pages 35-49
    5. Maja H. Oktay, Agnese Mariotti, Filippo G. Giancotti
      Pages 51-61
    6. Maximilian Schneller, Wadih Arap, Renata Pasqualini
      Pages 63-78
    7. Wadih Arap, H.-J. Su Huang
      Pages 91-101
  3. Functional Analysis of Integrins

    1. Front Matter
      Pages 103-103
    2. Rui Li, M. Amin Arnaout
      Pages 105-124
    3. Craig A. Steger, Mara Fornaro, Amy S. Woodard, Duo-Qi Zheng, Lucia R. Languino
      Pages 125-134
    4. Jan F. Talts, Cord Brakebusch, Reinhard Fässler
      Pages 153-187
    5. Emilio Hirsch, Piero Cervella, Lorenzo Silengo, Fiorella Altruda
      Pages 189-208
  4. Integrin Function at the Cellular Level

    1. Front Matter
      Pages 209-209
    2. James M. Wu, Mary P. Rosser, Anthony R. Howlett, Richard I. Feldman
      Pages 211-217
    3. Klaus von der Mark, Stephan Schöber, Simon L. Goodman
      Pages 219-230
    4. John T. Price, Erik W. Thompson
      Pages 231-249
    5. Steven M. Frisch
      Pages 251-256
    6. Peter C. Brooks, Anthony M. P. Montgomery, David A. Cheresh
      Pages 257-269
  5. Back Matter
    Pages 285-296

About this book


In Integrin Protocols, Anthony Howlett and a distinguished panel of experimentalists describe in detail a series of cutting-edge methods for dissecting the role of integrins in biological processes. This wide-ranging collection includes protocols for the analysis of integrin expression-at both the RNA and protein levels-and for elucidating the functional properties of integrins, including those at the cellular level. Each method provides step-by-step instructions for easy reproducibility, along with extensive notes about potential pitfalls, and tips on how to avoid failure. The emphasis is always on the practical steps necessary for experimental success and robust results.
Offering powerful tools for understanding how integrins regulate cell growth, differentiation, migration, invasion, angiogenesis, and apoptosis, as well as how abnormalities of integrin expression and function may be implicated in various pathologic conditions, Integrin Protocols constitutes a gold-standard collection of techniques for both new and experienced investigators of the molecular and cellular basis of cardiovascular disease, inflammatory disorders, and cancer.

Editors and affiliations

  • Anthony Howlett
    • 1
  1. 1.Berlex BiosciencesRichmondUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 1999
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-569-0
  • Online ISBN 978-1-59259-249-4
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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