© 2001

Meningococcal Disease

Methods and Protocols

  • John M. Walker
  • Andrew J. Pollard
  • Martin C. J. Maiden

Part of the Methods in Molecular Medicine™ book series (MIMM, volume 67)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Keith Cartwright
    Pages 1-8
  3. Malcolm Guiver, Ray Borrow
    Pages 23-39
  4. Michael A. Sobanski, Rosemary A. Barnes, W. Terence Coakley
    Pages 41-59
  5. Stephen J. Gray, Ray Borrow, Edward B. Kaczmarski
    Pages 61-87
  6. Colin Block
    Pages 89-106
  7. Martin C. J. Maiden, Norman T. Begg
    Pages 121-130
  8. Betsy Kuipers, Germie van den Dobbelsteen, Elisabeth Wedege, Loek van Alphen
    Pages 131-145
  9. Mark Achtman, Giovanna Morelli
    Pages 147-155
  10. Keith A. Jolley
    Pages 173-186
  11. Ulrich Vogel, Heike Claus, Matthias Frosch
    Pages 187-201
  12. Michael P. Jennings, Andrew W. Berrington, E. Richard Moxon
    Pages 203-214
  13. Alex C. Jeffries, Nigel J. Saunders, Derek W. Hood
    Pages 215-230
  14. Lucas D. Bowler, Aldert Bart, Arie van der Ende
    Pages 231-255
  15. James M. Stuart
    Pages 257-272
  16. Dominique A. Caugant
    Pages 273-292

About this book


Neisseria meningitidis is a major cause of childhood morbidity and mortality in industrialized nations and is responsible for epidemics of meningococcal meningitis and septic shock in Africa and Asia. In Meningococcal Disease: Methods and Protocols, Andrew Pollard and Martin Maiden bring together a panel of leading authorities to produce a comprehensive, interdisciplinary survey of recent advances and knowledge about this much-feared disease. The review and methods-based chapters collected here provide essential information for diagnosis in the clinical microbiology laboratory, isolate characterization, clinical management, and control of meningococcal disease. They also examine the immunopathological mechanisms occurring in the acutely ill, host-pathogen interactions, and the possible components of meningococcus responsible for virulence. A companion volume, Meningococcal Vaccines, provides detailed methods for the design and evaluation of meningococcal vaccines.
Comprehensive and authoritative, Meningococcal Disease: Methods and Protocols integrates the basic science and the clinical and epidemiological aspects of this terrible infectious disease to promote the deeper understanding needed to identify novel targets for therapeutic interventions and vaccines.


infectious diseases

Editors and affiliations

  • John M. Walker
  • Andrew J. Pollard
    • 1
  • Martin C. J. Maiden
    • 2
  1. 1.BC Research Institute for Children’s and Women’s HealthVancouverCanada
  2. 2.Wellcome Trust Centre for the Epidemiology of Infectious DiseaseOxfordUK

Bibliographic information

  • Book Title Meningococcal Disease
  • Book Subtitle Methods and Protocols
  • Editors Andrew J. Pollard
    Martin C.J. Maiden
  • Series Title Methods in Molecular Medicine™
  • DOI
  • Copyright Information Humana Press 2001
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Hardcover ISBN 978-0-89603-849-3
  • Softcover ISBN 978-1-61737-221-6
  • eBook ISBN 978-1-59259-149-7
  • Series ISSN 1543-1894
  • Series E-ISSN 1940-6037
  • Edition Number 1
  • Number of Pages XVII, 721
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Infectious Diseases
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Public Health
Internal Medicine & Dermatology


"The editors invited the most skilled specialists in the world, 95 contributors, to share with the readers their knowledge of many aspects of meningococcal disease....The book is a brilliant and comprehensive review of the most recent methods for investigation of meningococcal disease and Neisseria meningitidis. It also includes detailed protocols, which should contribute to standardization of meningococcal investigation in the whole world and should allow different laboratories to obtain comparable results. The book is an excellent source of references. It is highly recommended to microbiologists, epidemiologists and clinicians dealing with meningococcal disease." - Folia Microbiologia

"The book claims to be "a comprehensive and authoritative review of meningococcal biology", "an interdisciplinary survey of recent advances and knowledge", to give "cutting-edge methods for the diagnosis, epidemiology and treatment of meningococcal disease", and it fully meets these standards. It has achieved its aim to join basic science with epidemiological and clinical aspects of the disease." - International Journal of Medical Microbiology