© 2001


Experimental Methods and Protocols

  • Angela F. Drew

Part of the Methods in Molecular Medicine™ book series (MIMM, volume 52)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Rodney J. Dilley
    Pages 7-13
  3. Kishor M. Wasan, Shawn M. Cassidy, Allison L. Kennedy, Kathy D. Peteherych
    Pages 27-35
  4. Joan A. Higgins, John M. Graham, Ian G. Davies
    Pages 37-49
  5. John M. Graham, Bruce A. Griffin, Ian G. Davies, Joan A. Higgins
    Pages 51-59
  6. Andreas Ritsch, Josef R. Patsch
    Pages 61-76
  7. Roberto Accinni, Oberdan Parodi
    Pages 77-103
  8. Akira Tanaka
    Pages 105-111
  9. Michael Bender, Werner Gross
    Pages 113-122
  10. Eleni Papakonstantinou, Michael Roth, George Karakiulakis
    Pages 123-136
  11. Marisa A. Gallicchio
    Pages 137-146
  12. Marisa A. Gallicchio
    Pages 147-161
  13. George Karakiulakis, Eleni Papakonstantinou, Michael Roth
    Pages 163-169
  14. Marcy Silver, Jeffrey M. Isner
    Pages 207-211

About this book


Atherosclerosis-a major killer of people in Western societies-is not yet completely understood. In Atherosclerosis: Methods and Protocols, Angela Drew and a panel of experts have assembled a comprehensive collection of traditional and cutting-edge techniques for investigating this disease and its possible treatments. Each readily reproducible method includes step-by-step instructions and practical information regarding sample collection, the choice of animal model system, experimental design, and practical data analysis techniques. Assay systems for serum or plasma determination of lipoproteins are also described, along with assays for those plasma proteins recently identified as implicated in atherogenesis, including cholestryl ester transfer protein, homocysteine, glycated lipoproteins, and apolipoprotein(a). Additional techniques cover the isolation and culture of cells and glycosaminoglycans from atherosclerotic plaques, and the collection and analysis of experimental atherosclerotic lesions.
Comprehensive and richly detailed, Atherosclerosis: Methods and Protocols enables all biomedical investigators to select those optimized techniques that may be most fruitfully used to study the development, progression, and treatment of atherosclerotic lesions today.

Editors and affiliations

  • Angela F. Drew
    • 1
  1. 1.Children’s Hospital Research FoundationCincinnati

Bibliographic information

  • Book Title Atherosclerosis
  • Book Subtitle Experimental Methods and Protocols
  • Editors Angela F. Drew
  • Series Title Methods in Molecular Medicine™
  • DOI
  • Copyright Information Humana Press 2001
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Hardcover ISBN 978-0-89603-751-9
  • Softcover ISBN 978-1-61737-168-4
  • eBook ISBN 978-1-59259-073-5
  • Series ISSN 1543-1894
  • Series E-ISSN 1940-6037
  • Edition Number 1
  • Number of Pages XI, 247
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Cardiology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


"Methods for setting up animal model periments and special assays of blood and cellular moments of the pathologic processes involved are thoroughly described and referenced. Newly emerging animal models based on genetic manipulation are described in depth, with sufficient detail to broaden the scope of research by seasoned investigators to permit the novice to enter this field. ...Anyone working in vascular pathology and atherosclerosis research will find a wealth of practical information describing modern research methods." - Clinical and Applied Thrombosis/Hemostasis

"Atherosclerosis is recommended for academic health science libraries. It is also recommended to individual laboratories that conduct research in the area of atherosclerosis or heart disease." -E-STREAMS