Clinical Applications of PCR

  • Y. M. Dennis Lo

Part of the Methods in Molecular Medicine™ book series (MIMM, volume 16)

Table of contents

  1. Front Matter
    Pages i-x
  2. Introduction

    1. Y. M. Dennis Lo
      Pages 11-17
  3. General Methodology

    1. Y. M. Dennis Lo
      Pages 21-25
    2. Luc Raeymaekers
      Pages 27-38
    3. Philip J. Saker
      Pages 39-49
    4. Y. M. Dennis Lo
      Pages 61-69
    5. Y. M. Dennis Lo, Virginia A. Horton
      Pages 71-79
    6. William Waggott
      Pages 81-91
    7. Y. M. Dennis Lo, Shu F. An
      Pages 93-100
    8. John O’Leary
      Pages 109-144
    9. Paul Moss, Swee Lay Thein
      Pages 145-148
  4. Clinical Application

  5. Back Matter
    Pages 341-353

About this book


Clinical Applications of PCR offers an unprecedented collection of core PCR techniques for the study and diagnosis of human diseases. Cutting-edge and essential for today's diagnostic laboratories, these techniques heavily utilize nonisotopic, solution phase, and in situ amplification methods. A significant number of chapters describe applications exploiting the exquisite sensitivity of PCR in the detection of rare or single cells, as in identifying fetal cells circulating in maternal blood, preimplantation embryo diagnosis, or detecting circulating cancer cells.
The methods described in Clinical Applications of PCR will well serve diverse clinical specialties ranging from hematology/oncology, human genetics, and microbiology, to virology, pathology, and infectious diseases. The book repeatedly demonstrates the power of PCR-its high sensitivity, specificity, and ability to rapidly discriminate sequence variations.

Editors and affiliations

  • Y. M. Dennis Lo
    • 1
  1. 1.The Chinese University of Hong KongHong Kong SAR

Bibliographic information

  • DOI
  • Copyright Information Humana Press 1998
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-499-0
  • Online ISBN 978-1-59259-600-3
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • Buy this book on publisher's site
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