© 1996

Prion Diseases

  • Harry F. Baker
  • Rosalind M. Ridley

Part of the Methods in Molecular Medicine book series (MIMM, volume 3)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Rosalind M. Ridley, Harry F. Baker
    Pages 1-13
  3. Rajith de Silva
    Pages 15-33
  4. Robert G. Will
    Pages 119-137
  5. John W. Wilesmith
    Pages 155-173
  6. David A. J. Tyrrell, Kevin C. Taylor
    Pages 175-198
  7. Jonathon R. Gray, Jo R. Soldan, Peter S. Harper
    Pages 199-210
  8. Moira E. Bruce
    Pages 223-236
  9. Fabrizio Tagliavini, Frances Prelli, Giorgio Giaccone, Gianluigi Forloni, Mario Salmona, Pedro Piccardo et al.
    Pages 265-283
  10. Byron Caughey, David A. Kocisko, Suzette A. Priola, Gregory J. Raymond, Richard E. Race, Richard A. Bessen et al.
    Pages 285-299
  11. Martin Jeffrey, Caroline M. Goodsir
    Pages 301-312
  12. Back Matter
    Pages 313-317

About this book


In Prion Diseases leading researchers and clinicians describe their state-of-the-art findings and hypotheses arising from a variety of different approaches to this group of diseases. Their approaches include clinical presentations, epidemiology, transgenic methods, and diagnostic tests via transmission electron microscopy and immunoblotting. The diseases covered include human and animal spongiform encephalopathies, such as Creutzfeldt-Jakob disease, mad cow disease, and scrapie.

Prion Diseases illuminates the conflicting hypotheses that have evolved to explain these diverse disorders which can appear as infectious diseases a genetically determined diseases, as well as ones sharing neuropathological similarities with such common neurodegenerative diseases as Alzheimer's disease, Parkinson's disease, and amyotropic lateral sclerosis. It provides a much-needed overview of various approaches to understanding these diseases by showing how researchers have analyzed their different facets, ranging from the epidemiology of the human versions to molecular genetics of the animal forms of the diseases.

Editors and affiliations

  • Harry F. Baker
    • 1
  • Rosalind M. Ridley
    • 1
  1. 1.Cambridge UniversityCambridgeUK

Bibliographic information

  • Book Title Prion Diseases
  • Editors Harry F. Baker
    Rosalind M. Ridley
  • Series Title Methods in Molecular Medicine
  • DOI
  • Copyright Information Humana Press 1996
  • Publisher Name Springer, Totowa, NJ
  • eBook Packages Springer Protocols
  • Hardcover ISBN 978-0-89603-342-9
  • Softcover ISBN 978-1-4899-4040-7
  • eBook ISBN 978-1-59259-587-7
  • Series ISSN 1543-1894
  • Series E-ISSN 1940-6037
  • Edition Number 1
  • Number of Pages XV, 319
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Cell Biology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals


Prion Diseases is a timely publication...Scientists already established in the subject as well as those embarking on such research for the first time will find the book useful. I also recommend it as a well structured text..-British Medical Journal