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Chromosome Analysis Protocols

  • John R. Gosden

Part of the Methods in Molecular Biology™ book series (MIMB, volume 29)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Ann C. Chandley, Robert M. Speed, Kun Ma
    Pages 27-40
  3. Adrian T. Sumner, Andrew R. Ross, Elizabeth Graham
    Pages 41-50
  4. Judy Fletcher
    Pages 51-57
  5. Adrian T. Sumner
    Pages 83-96
  6. Dieter Schweizer, Peter F. Ambros
    Pages 97-112
  7. Adrian T. Sumner, Arthur R. Mitchell
    Pages 113-121
  8. Joaquina de la Torre, Adrian T. Sumner
    Pages 123-139
  9. Jim Graham, Jim Piper
    Pages 141-185
  10. Judith A. Fantes, Daryll K. Green, Andrew Sharkey
    Pages 205-219
  11. Christa Heyting, Axel J. J. Dietrich, J. de Hans Jong, Edgar Hartsuiker
    Pages 287-302
  12. Veronica van Heyningen
    Pages 303-322
  13. Sandya Narayanswami, Barbara A. Hamkalo
    Pages 335-351
  14. David J. Porteous
    Pages 353-378
  15. Steven D. M. Brown, Alyson H. Carey
    Pages 425-436
  16. David L. Saltman, Stephen P. Hunger, Gillian E. Turner
    Pages 437-448
  17. Peter Lichter, Thomas Ried
    Pages 449-478
  18. John Gosden, Matthew Breen, Diane Lawson
    Pages 479-492
  19. Robin C. Allshire, Howard J. Cooke
    Pages 493-503
  20. Back Matter
    Pages 505-508

About this book

Introduction

Chromosomes, as the genetic vehicles, provide the basic material for a large proportion of genetic investigations, from the construction of gene maps and models of chromosome organization, to the inves­ tigation of gene function and dysfunction. The study of chromosomes has developed in parallel with other aspects of molecular genetics, beginning with the first preparations of chromosomes from animal cells, through the development of banding techniques, which permitted the unequivocal identification of each chromosome in a karyotype, to the present analytical methods of molecular cytogenetics. Although some of these techniques have been in use for many years, and can be learned relatively easily, most published scientific reports—as a result of pressure on space from editors, and the response to that pressure by authors—contain little in the way of technical detail, and thus are rarely adequate for a researcher hoping to find all the necessary information to embark on a method from scratch. A new user needs not only a detailed description of the methods, but also some help with problem solving and sorting out the difficulties en­ countered in handling any biological system. This was the require­ ment to which the series Methods in Molecular Biology is addressed, and Chromosome Analysis Protocols forms a part of this series.

Editors and affiliations

  • John R. Gosden
    • 1
  1. 1.Medical Research CouncilEdinburghScotland

Bibliographic information

  • DOI https://doi.org/10.1385/0896032892
  • Copyright Information Humana Press 1994
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-289-7
  • Online ISBN 978-1-59259-516-7
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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