Peptide Synthesis Protocols

  • Michael W. Pennington
  • Ben M. Dunn

Part of the Methods in Molecular Biology book series (MIMB, volume 35)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Michael W. Pennington, Michael E. Byrnes
    Pages 1-16
  3. Gregg B. Fields
    Pages 17-27
  4. Cynthia G. Fields, Gregg B. Fields
    Pages 29-40
  5. Frank A. Robey
    Pages 73-90
  6. David Andreu, Fernando Albericio, Núria A. Solé, Mark C. Munson, Marc Ferrer, George Barany
    Pages 91-169
  7. Michael W. Pennington
    Pages 171-185
  8. Victor J. Hruby, Xinhua Qian
    Pages 249-286
  9. Monika Mergler
    Pages 287-301
  10. Rolf Nyfeler
    Pages 303-316
  11. Back Matter
    Pages 317-321

About this book


Peptide synthesis has emerged as one of the most powerful tools in biochemical, pharmacological, immunological, and biophysical la- ratories. Recent improvements include general solid-phase method- ogy, new protecting groups, and automated equipment. These advances have allowed the facile synthesis of increasingly more complex p- tides. Many of these new and improved methods for the synthesis of peptides and peptide-related substances have been reported in various publications, but never compiled in a convenient handbook. Like other volumes in this series, Peptide Synthesis Protocols concentrates on the practical aspects of these procedures, providing the researcher with detailed descriptions and helpful tips about potential problems. This volume is not intended to serve as a basic guide to standard Merrifie- type solid-phase strategy, but rather to provide the researcher with some of the most recent applications in the field of peptide science. A c- panion volume, Peptide Analysis Protocols, will detail methodology for the charaterization of new synthetic peptides. Development of new methods and applications has continued actively even as this volume was in preparation. Owing to the number of contributors to this volume, it was necessary to establish a cutoff for publication purposes. We feel that all of the protocols presented are timely and up-to-date. Several promising new strategies, such as allyloxycarbonyl-based syntheses, were being developed at the time this volume was in the editing stages and will be included in future editions.

Editors and affiliations

  • Michael W. Pennington
    • 1
  • Ben M. Dunn
    • 2
  1. 1.Bachem BioscienceKing of PrussiaUSA
  2. 2.University of FloridaGainesvilleUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 1995
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-273-6
  • Online ISBN 978-1-59259-522-8
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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