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Interventions for Persisting Ductus Arteriosus in the Preterm Infant

  • Book
  • © 2005

Overview

Editors:
  1. Michael Obladen

    1. Department of Neonatology, Charité Universitätsmedizin Berlin, Campus Virchow/Campus Benjamin Franklin, Berlin

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  2. Petra Koehne

    1. Department of Neonatology, Charité Universitätsmedizin Berlin, Campus Virchow, Berlin

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    You can also search for this editor in PubMed   Google Scholar

  • Only book dealing specifically with the ductus arteriosus

  • Gives current state of the art

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Table of contents (18 chapters)

  1. Front Matter

    Pages I-XI
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  2. Basics

    1. Developmental Anatomy of the Ductus Arteriosus

      • Regina Bökenkamp
      Pages 2-5

    2. Regulation of Smooth Muscle Contraction

      • Ingo Morano
      Pages 6-11

    3. Prostaglandin Metabolism and Effects of Inhibitors

      • Karsten Schrör
      Pages 12-14

    4. Postnatal Circulatory Adaptation

      • Michael Hofbeck
      Pages 15-18

    5. Epidemiology of Persisting Ductus in Preterm Infants

      • Christiane Pees, Michael Obladen
      Pages 19-23

  4. Diagnostics

    1. Echocardiographic Assessment

      • Helmut Singer
      Pages 40-44

    2. Cerebral Doppler Sonographic Measurements

      • Karl-Heinz Deeg, Burkhard Trusen
      Pages 45-49

  5. Interventions

    1. Therapeutic Options

      • Axel von der Wense
      Pages 52-56

    2. Surgical Closure

      • Michael Hübler
      Pages 57-64

    3. Comparison of Indomethacin and Ibuprofen

      • Bart van Overmeire
      Pages 65-68

    4. Indomethacin Effects and Side Effects

      • Berndt Urlesberger
      Pages 69-73

    5. Complications of Cyclooxygenase Inhibition in Preterm Infants

      • Véronique Gournay
      Pages 74-83

    6. Ibuprofen in Infants Below 28 Gestational Weeks

      • Petra Koehne
      Pages 84-91

    7. Intravenous Ibuprofen: State of Registration

      • Marie Christine Fortun
      Pages 92-92

  6. Perspectives

    1. Summary and Perspectives

      • Michael Obladen
      Pages 94-97

  7. Back Matter

    Pages 98-103
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Keywords

About this book

Over the past few years a remarkably rapid evolution in the professional level of neonatology and in the survival of immature infants has been witnessed. Persisting ductus arteriosus is common in this population and is associated with impaired longterm outcome. Many uncertainties exist concerning indication, approach, best time, and side effects of necessary measurements and interventions to avoid later neurodevelopmental handicaps of the survivors.

Experts in neonatology and pediatric cardiology give their opinion in this book. We are sure it will help to define the level of evidence and to develop standards of intervention for persisting ductus arteriosus in Europe. Adequate dealing with the ductus will become a challenge for every perinatal center.

Editors and Affiliations

  • Department of Neonatology, Charité Universitätsmedizin Berlin, Campus Virchow/Campus Benjamin Franklin, Berlin

    Michael Obladen

  • Department of Neonatology, Charité Universitätsmedizin Berlin, Campus Virchow, Berlin

    Petra Koehne

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