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Quasispecies: Concept and Implications for Virology

  • Book
  • © 2006

Overview

Editors:
  1. Esteban Domingo

    1. Centro de BiologÍa Molecular “Servero Ochoa” (CSIC-UAM), Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain

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  • Begins from the understanding that virus variation and selection in virus subpopulations are intimately related to viral disease mechanisms
  • A central topic is the origin of the quasispecies concept
  • Examines the implications of quasispecies dynamics for viral populations
  • Presents and analyzes vital new research in the evolution of viral diseases
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 299)

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Table of contents (14 chapters)

  1. Front Matter

    Pages I-XI
    Download chapter PDF

  2. What Is a Quasispecies?

    • C. K. Biebricher, M. Eigen
    Pages 1-31

  3. Quasispecies in Time-Dependent Environments

    • C. O. Wilke, R. Forster, I. S. Novella
    Pages 33-50

  4. Viruses as Quasispecies: Biological Implications

    • E. Domingo, V. Martín, C. Perales, A. Grande-Pérez, J. García-Arriaza, A. Arias
    Pages 51-82

  5. Virus Fitness: Concept, Quantification, and Application to HIV Population Dynamics

    • M. E. Quiñones-Mateu, E. J. Arts
    Pages 83-140

  6. Population Bottlenecks in Quasispecies Dynamics

    • C. Escarmís, E. Lázaro, S. C. Manrubia
    Pages 141-170

  7. Evolutionary Dynamics of HIV-1 and the Control of AIDS

    • J. I. Mullins, M. A. Jensen
    Pages 171-192

  8. Evolution of Virulence in Picornaviruses

    • S. Tracy, N. M. Chapman, K. M. Drescher, K. Kono, W. Tapprich
    Pages 193-209

  9. Molecular Mechanisms of Poliovirus Variation and Evolution

    • V. I. Agol
    Pages 211-259

  10. Hepatitis C Virus Population Dynamics During Infection

    • J.-M. Pawlotsky
    Pages 261-284

  11. Evolutionary Influences in Arboviral Disease

    • S. C. Weaver
    Pages 285-314

  12. Arenavirus Diversity and Evolution: Quasispecies In Vivo

    • N. Sevilla, J. C. de la Torre
    Pages 315-335

  13. Mutant Clouds and Occupation of Sequence Space in Plant RNA Viruses

    • M. J. Roossinck, W. L. Schneider
    Pages 337-348

  14. Parvovirus Variation for Disease: A Difference with RNA Viruses?

    • A. López-Bueno, L. P. Villarreal, J. M. Almendral
    Pages 349-370

  15. Transitions in Understanding of RNA Viruses: A Historical Perspective

    • J. J. Holland
    Pages 371-401

  16. Back Matter

    Pages 403-410
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Keywords

About this book

Continuous genetic variation and selection of virus subpopulations in the course of RNA virus replications are intimately related to viral disease mechanisms. The central topics of this volume are the origins of the quasispecies concept, and the implications of quasispecies dynamics for viral populations.

Editors and Affiliations

  • Centro de BiologÍa Molecular “Servero Ochoa” (CSIC-UAM), Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain

    Esteban Domingo

Bibliographic Information

  • Book Title: Quasispecies: Concept and Implications for Virology

  • Editors: Esteban Domingo

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/b137531

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2006

  • Hardcover ISBN: 978-3-540-26395-1Published: 21 December 2005

  • Softcover ISBN: 978-3-642-06582-8Published: 12 February 2010

  • eBook ISBN: 978-3-540-26397-5Published: 19 February 2006

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XI, 410

  • Topics: Virology

  • Industry Sectors: Biotechnology, Pharma

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