Overview
- Covers the latest aspects of mitochondrial biogenesis, genome evolution, metabolism and energy generation
- Provides a new link between basic mitochondrial research and mitochondrial medicine
Part of the book series: Topics in Current Genetics (TCG, volume 8)
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Table of contents (13 chapters)
Keywords
- Mitochondrial Biogenesis
- Mitochondrial Energy Generation
- Mitochondrial Genome Evolution
- Mitochondrial Metabolic Pathway
- Mitochondrial Morphology
- Mitochondrial Structure
- ATP
- biochemistry
- chemistry
- development
- genetics
- genome
- membrane
- metabolism
- mitochondria
- morphology
- Organelle
- phosphorylation
- protein
- synthesis
- tRNA
About this book
Mitochondria are complex organelles, possessing a double-membrane and even their own genome, the mtDNA. They play a pivotal role in cellular metabolism, respiration, and production of ATP essential for the normal function of all human organ systems. It is not surprising, therefore, that genetic defects of mitochondrial functions cause a wide spectrum of human diseases. This book provides the first modern and truly comprehensive coverage of the biochemistry, genetics, and pathology of mitochondria in different organisms. It particularly focuses on the recent advances in our understanding of basic mitochondrial research to the consequences of dysfunction at the molecular level.
The 13 contributions written by leading researchers in the field include topics such as: mitochondrial genome evolution and mtDNA stability, mitochondrial biogenesis and protein quality control, mitochondrial morphology, assembly and function of the mitochondrial energy generation apparatus and mitochondrial metabolic pathways. These are particularly oriented to link in these various mitochondrial pathways to the clinical consequences of their dysfunctions.
Editors and Affiliations
Bibliographic Information
Book Title: Mitochondrial Function and Biogenesis
Editors: Carla Koehler, Matthias F. Bauer
Series Title: Topics in Current Genetics
DOI: https://doi.org/10.1007/b10825
Publisher: Springer Berlin, Heidelberg
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eBook Packages: Springer Book Archive
Copyright Information: Springer-Verlag Berlin Heidelberg 2004
Hardcover ISBN: 978-3-540-21489-2Published: 13 May 2004
Softcover ISBN: 978-3-642-05994-0Published: 15 December 2010
eBook ISBN: 978-3-540-40895-6Published: 03 March 2004
Series ISSN: 1610-2096
Series E-ISSN: 1610-6970
Edition Number: 1
Number of Pages: XVI, 333
Topics: Biochemistry, general, Cell Biology, Human Genetics
Industry Sectors: Biotechnology, Consumer Packaged Goods, Pharma