Management of Infectious Complication in Cancer Patients

1. Front Matter

   Pages i-xi

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2. Host impairments in patients with neoplastic diseases

   • Ben E. De Pauw, J. Peter Donnelly, Bart-Jan Kullberg

   Pages 1-32

3. Epidemiology of infectious complications in cancer patients

   • Teresa Zembower

   Pages 33-75

4. Approach to fever in the neutropenic host

   • Athena Stoupis, Stephen H. Zinner

   Pages 77-104

5. Infections associated with solid tumors

   • Sarah H. Sutton, John P. Flaherty

   Pages 105-141

6. Role of the clinical microbiology laboratory in the diagnosis of infections

   • Richard B. Thomson Jr., Lance R. Peterson

   Pages 143-165

7. Recent advances in the management of fungal infections

   • Jason Sanchez, Gary A. Noskin

   Pages 167-182

8. Recent advances in the management of viral infections

   • John R. Wingard

   Pages 183-200

9. Cytokines and biological response modifiers in the treatment of infection

   • Brigitta U. Mueller, Phillip A. Pizzo

   Pages 201-222

10. Prevention of infection in immunocompromised hosts

    • Gary A. Noskin

    Pages 223-246

11. Pharmacologic considerations with antimicrobials used in oncology

    • Michael Postelnick, Sara R. Halbur

    Pages 247-282

12. Economic impact of infections in patients with cancer

    • David J. Shulkin, Lawrence J. Anastasi

    Pages 283-290

13. Back Matter

    Pages 291-300

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Infection is a major cause of morbidity and mortality in patients with neoplastic disease because of compromised host defenses. These defects result in an increased risk of infection and its complications. The nature of the underlying malignancy, the immunodeficiencies associated with it, and the treatments directed against it are all important determinants of infection. In recent years, the introduction of more intensive chemotherapeutic regimes and the widespread use of bone marrow and peripheral stem cell transplantation have changed the pattern of infection in many patients. Furthermore, the increasing use of central venous access devices and antimicrobial prophylaxis has changed the epidemiology of infection in these patients as well.
The goal of this volume in the Cancer Treatment and Research series is to emphasize that while the management of infection in cancer patients is common, it is constantly changing. With the increasing complexity of these patients, optimal management requires a multidisciplinary approach. Ultimately, it is hoped that this book will assist clinicians in the diagnosis, management, and prevention of infection in order to optimize care for patients with cancer.

• antimicrobial
• antimicrobial prophylaxis
• fungal infection
• infection
• infections
• infectious
• viral infection
• infectious diseases

`... this book presents a good, sound overview of multiple concepts in infectious complications in oncology, with well written, logical chapters. It has excellent tables throughout and its multidisciplinary approach is a plus.'
Cancer Forum, 24:1 (2000)

• Northwestern Medical University School, Chicago

  Gary A. Noskin

• Infection Control Healthcare Epidemiology, Northwestern Memorial Hospital, Chicago

  Gary A. Noskin

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