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  • Book
  • © 2019

Autophagy: Biology and Diseases

Basic Science

Editors:

  • focusing on the biology of autophagy
  • Systematically summarizing the cutting-edge knowledge in the basic study of autophagy
  • Serving as a critical reference tool for researchers and clinicians
  • With ample illustrations

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1206)

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Table of contents (30 chapters)

  1. Front Matter

    Pages i-xv
  2. History and Current Status of Autophagy Research

    1. Front Matter

      Pages 1-1
    2. History and Current Status of Autophagy Research

      • Rui Sheng, Zheng-Hong Qin
      Pages 3-37
  3. Regulation of Autophagy

    1. Front Matter

      Pages 39-39
    2. Regulation of ATG and Autophagy Initiation

      • Wen Li, Lining Zhang
      Pages 41-65
    3. Regulation of Autophagy by mTOR Signaling Pathway

      • Ying Wang, Hongbing Zhang
      Pages 67-83
    4. AMPK and Autophagy

      • Yanjun Li, Yingyu Chen
      Pages 85-108
    5. Beclin 1, Bcl-2 and Autophagy

      • Hai-Dong Xu, Zheng-Hong Qin
      Pages 109-126
    6. TP53, TP53 Target Genes (DRAM, TIGAR), and Autophagy

      • Wanglai Hu, Song Chen, Rick F. Thorne, Mian Wu
      Pages 127-149
    7. Ca(2+) Ion and Autophagy

      • Yang-Xi Hu, Xiao-Shuai Han, Qing Jing
      Pages 151-166
    8. Endoplasmic Reticulum Stress and Autophagy

      • Zhihao Qi, Linxi Chen
      Pages 167-177
    9. Oxidative Stress and Autophagy

      • Qi Gao
      Pages 179-198
    10. Non-coding RNAs and Autophagy

      • Honghong Yao, Bing Han, Yuan Zhang, Ling Shen, Rongrong Huang
      Pages 199-220
    11. Epigenetic Regulation of Autophagy

      • Li-Fang Hu
      Pages 221-236
    12. Protein Modification and Autophagy Activation

      • Rui Wang, Guanghui Wang
      Pages 237-259
    13. Other Molecular Mechanisms Regulating Autophagy

      • Nan Zhang, Ying Zhao
      Pages 261-271
    14. The Role of Nanomaterials in Autophagy

      • Min Wei, Wei-Dong Le
      Pages 273-286
    15. Structural Basis of Autophagy Regulatory Proteins

      • Lifeng Pan, Jianping Liu, Ying Li
      Pages 287-326
  4. Biological Function of Autophagy

    1. Front Matter

      Pages 327-327
    2. Autophagy and Energy Metabolism

      • Jie Yang, Ruimin Zhou, Zhenyi Ma
      Pages 329-357

About this book

This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy.

Volume 1 focuses on the biology of autophagy, including the signaling pathways, regulating processes and biological functions. Autophagy is a fundamental physiological process in eukaryotic cells. It not only regulates normal cellular homeostasis, and organ development and function, but also plays an important role in the pathogenesis of a wide range of human diseases. Thanks to the rapid development of molecular biology and omic technologies, research on autophagy has boomed in recent decades, and more and more cellular and animal models and state-of the-art technologies are being used to shed light on the complexity of signaling networks involved in the autophagic process. Further, its involvement in biological functions and the pathogenesis of various diseases has attracted increased attention around the globe. Presenting cutting-edge knowledge, this book series is a useful reference resource for researchers and clinicians who are working on or interested in autophagy.


Editors and Affiliations

  • Jiangsu Key Laboratory of Neuropsychiatric Diseases, Department of Pharmacology and Laboratory of Aging and Nervous Diseases, College of Pharmaceutical Sciences of Soochow University, Suzhou, China

    Zheng-Hong Qin

About the editor

Dr. Zheng-Hong Qin is a Professor of Pharmacology at the School of Pharmaceutical Sciences, Soochow University. He is also the Director of the Laboratory of Aging and Nervous Diseases, Soochow University. Prof. Qin holds positions in several academic societies, including Associate Director of the Anti-aging Branch of the Chinese Society of Gerontology and Geriatrics, and committee member of the Biochemical and Molecular Pharmacology Branch and Neuro- and Psycho-pharmacology Branch of the Chinese Neuroscience Society. He serves on the editorial board of Acta Pharmacologica Sinica. Prof. Qin’s research focuses on aging and age-related neurological disorders and drug development from venoms. A pioneer in the field of autophagy in China, he has published more than 200 articles and was listed as the most-cited Chinese scholar in 5 consecutive years, from 2014 to 2018. 


Bibliographic Information

Buy it now

Buying options

eBook USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access