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  • © 2019

Structural Immunology

  • Presenting a comprehensive overview of important immune molecules and their structure-function relationships
  • Providing researchers and students with the latest research advances concerning the structural biology of some key immune molecules/pathways
  • Offering immunologists essential insights into how these immune molecules function

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1172)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xiii
  2. Structural Basis for Signaling Through Shared Common γ Chain Cytokines

    • Huilin Yang, Rakeeb Kureshi, Jamie B. Spangler
    Pages 1-19
  3. Interleukin-10 Family Cytokines Immunobiology and Structure

    • Huaxing Wei, Bofeng Li, Anyuan Sun, Feng Guo
    Pages 79-96
  4. Structural Biology of NOD-Like Receptors

    • Xinru Yang, Guangzhong Lin, Zhifu Han, Jijie Chai
    Pages 119-141
  5. AIM2 Inflammasome Assembly and Signaling

    • Bing Wang, Yuan Tian, Qian Yin
    Pages 143-155
  6. NF-κB, IκB, and IKK: Integral Components of Immune System Signaling

    • Maria Carmen Mulero, Tom Huxford, Gourisankar Ghosh
    Pages 207-226

About this book

This book presents a comprehensive overview of important immune molecules and their structure-function relationships. The immune system is highly complex, consisting of a network of molecules, cells, tissues and organs, and the immune reaction is involved in various physiological as well as pathological processes, including development, self-tolerance, infection, immunity, and cancer. Numerous molecules participate in immune recognition, inhibition and activation, and these important immune molecules can be roughly divided into cell surface receptors, intracellular receptors and intracellular signaling molecules. The study of how these immune molecules function at molecular level has laid the foundation for understanding the immune system. The book provides researchers and students with the latest research advances concerning the structural biology of key immune molecules/pathways, and offers immunologists essential insights into how these immune molecules function.


Editors and Affiliations

  • The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China

    Tengchuan Jin

  • Department of Biological Science, Florida State University, Tallahassee, USA

    Qian Yin

About the editors

Dr. Tengchuan Jin is a Professor at the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China (USTC). He holds a Ph.D. degree from the Illinois Institute of Technology and completed his postdoctoral training at the Laboratory of Immunology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), USA. His current research interests include the structural biology of the innate immune receptors, structure and function of inflammasome, molecular mechanism of microbe-host interactions, protein engineering and antibody drug development, and he has published more than 50 research articles in these fields.

Dr. Yin Qian is currently an Assistant Professor at the Department of Biological Science, Florida State University. She received her Ph.D. degree from Cornell University and completed her postdoctoral training at Cornell University and Harvard Medical School underProf. Hao Wu, a well-known structural immunologist. Dr. Qian's research interests include the activation mechanism of interferon-inducible GTPases and regulatory mechanisms of Rag GTPases in autophagy. She has published a series of high-profile research articles in the field of structural immunology.

Bibliographic Information

Buy it now

Buying options

eBook USD 119.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 159.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access