Department of Molecular Biology and Biochemistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
This textbook uses a case-study approach to present the core principles of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care. The 29 clinical cases have been carefully selected to cover key scientific concepts and some common, and other not so common, diseases. While the principal focus is on topics relating to metabolic disease, further subjects such as connective tissue disorders, neurological disorders, auto-inflammatory disorders, infective diseases, and cancer are also addressed. Each chapter provides a specific patient report that includes the natural history, pertinent clinical laboratory data, physical findings, subsequent diagnosis, and therapy. This is followed by a comprehensive discussion of the normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease. Graphical diagrams are provided in each chapter for ease of comprehension.
Reviews
“The book's emphasis is on its role and importance in ‘bench‐to‐bedside’ training of healthcare professionals with the hope that this approach will have wide appeal in many disciplines related to pathobiochemistry. … This unique book combines biochemistry with molecular biology and presents various disorders in a case study format. This is indeed a unique strategy to present complex information. I am quite confident that medical students, researchers, clinicians and other healthcare professionals will find this book very useful.” (Omer Iqbal, Doody's Book Reviews, 27 September, 2019)
Editors and Affiliations
Department of Molecular Biology and Biochemistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
Toshitaka Oohashi
Department of Pediatrics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
Hirokazu Tsukahara
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, USA
Francesco Ramirez
Department of Biology College of Arts and Sciences, California Lutheran University, Thousand Oaks, USA
Chad L. Barber
Department of General Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
Fumio Otsuka
About the editors
Toshitaka Oohashi, Ph.D., Professor of Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Hirokazu Tsukahara, M.D., Ph.D., Professor of Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Francesco Ramirez, Ph.D., Professor of Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA
Chad Barber, Ph.D., Assistant Professor of Biology: California Lutheran University, Thousand Oaks, CA 91360, USA
Fumio Otsuka, M.D., Ph.D., Professor of Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Bibliographic Information
Book Title: Human Pathobiochemistry
Book Subtitle: From Clinical Studies to Molecular Mechanisms
Editors: Toshitaka Oohashi, Hirokazu Tsukahara, Francesco Ramirez, Chad L. Barber, Fumio Otsuka
