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  • © 2018

The Hair Fibre: Proteins, Structure and Development

  • Is the first book that brings together decades of research on keratin biochemistry and fibre
  • Fills a gap in the market for a research book in the scientific, cosmetic and medical areas
  • Has contributions from globally recognized experts in their field

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1054)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-viii
  2. Introduction to Hair and Follicles

    1. Front Matter

      Pages 1-1
    2. Fibre Ultrastructure

      • Jeffrey E. Plowman, Duane P. Harland
      Pages 3-13
    3. The Follicle Cycle in Brief

      • Jeffrey E. Plowman, Duane P. Harland
      Pages 15-17
  3. Hair Proteins

    1. Front Matter

      Pages 19-19
    2. Evolution of Trichocyte Keratins

      • Leopold Eckhart, Florian Ehrlich
      Pages 33-45
    3. Evolution of Trichocyte Keratin Associated Proteins

      • Dong-Dong Wu, David M. Irwin
      Pages 47-56
    4. Structural Hierarchy of Trichocyte Keratin Intermediate Filaments

      • R. D. Bruce Fraser, David A. D. Parry
      Pages 57-70
    5. Trichocyte Keratin-Associated Proteins (KAPs)

      • R. D. Bruce Fraser, David A. D. Parry
      Pages 71-86
  4. Hair Development

    1. Front Matter

      Pages 87-87
    2. Introduction to Hair Development

      • Duane P. Harland
      Pages 89-96
    3. Environment of the Anagen Follicle

      • Duane P. Harland
      Pages 97-108
    4. Development of Hair Fibres

      • Duane P. Harland, Jeffrey E. Plowman
      Pages 109-154
    5. Macrofibril Formation

      • Duane P. Harland, A. John McKinnon
      Pages 155-169
  5. Hair Chemistry and Thermodynamics

    1. Front Matter

      Pages 171-171
    2. The Thermodynamics of Trichocyte Keratins

      • Crisan Popescu
      Pages 185-203
    3. Oxidative Modification of Trichocyte Keratins

      • Jolon M. Dyer
      Pages 205-218
  6. Back Matter

    Pages 219-225

About this book

Hair is a sophisticated bio-based material, whether it is on a human head or part of a mammalian coat. In particular, the role of the proteins in the follicle, integral to hair development, are not well understood. This new book seeks to integrate the latest research in proteomic and morphological studies into a coherent description of fibre development from the follicle to its final mature, keratinized form.

To achieve this the book has been divided into three sections.  The first describes the keratins, their associated proteins and how they assemble into intermediate filaments in the fibre. The second covers the latest information on the morphological changes that occur from the base of the follicle, through the keratinization process to the mature fibre and the role that proteins play in this. The final section delves into fundamental fibre properties such as crosslinking, thermal and oxidative modifications and how these affect the mature fibre.

The editors of this book are internationally recognised for their work in the area of mammalian hair, Jeffrey Plowman for his knowledge of the proteomics of the fibre, Santanu Deb-Choudhury for his work in the area of crosslinking in the fibre and Duane Harland for his understanding of the morphological development of the fibre. Together they have collected material from other international experts: Leopold Eckhart and Florian Ehrlich for their knowledge of the evolution of keratins; Dong Dong Wu and David Irwin for their studies on keratin associated protein evolution; David Parry and Bruce Fraser for their work on keratin and keratin associated protein structure and assembly; John McKinnon for his studies on macrofibril formation; Crisan Popescu for the thermodynamics of keratins; and Jolon Dyer for his oxidative modification studies of keratins.

This book provides a comprehensive introduction, and useful reference guide to hair biology and will be of interest to both scientists and technologists.

Editors and Affiliations

  • AgResearch Ltd., Lincoln, New Zealand

    Jeffrey E. Plowman, Duane P. Harland, Santanu Deb-Choudhury

Bibliographic Information

Buy it now

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access