Overview
Elucidates the latest progress in chemotherapy for leukemia and related diseases
Presents prospective results of basic and preclinical studies for leukemia
Maximizes reader insight into modern treatment methodology for leukemia
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Table of contents (20 chapters)
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New Chemotherapeutic Agents Including Antimetabolite
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Therapy Targeting Leukemic Stem Cells
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Front Matter
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Keywords
About this book
This book focuses on the latest progress in chemotherapy for leukemia and related diseases, including still-ongoing but promising studies. The effectiveness of treatment for chronic myeloid leukemia and acute promyelocytic leukemia has been dramatically improved in recent years. This improvement has been made possible with the development of molecular targeted agents such as bcr-abl tyrosine kinase inhibitors and all-trans retinoic acid. The antibody for the unique target of chemokine receptor 4 for adult T-cell leukemia/lymphoma, or FLT3 inhibitors (signaling inhibitors) has been applied to other leukemias. Also, chemotherapeutic agents including antimetabolite analogues such as clofarabine, and azacitidine (an epigenetic regulator) have undergone progressive development. Meanwhile, the novel concept of therapy targeting leukemic stem cells has been developed. The contributors discuss prospective results of basic and preclinical studies and clinical possibilities based on the effects for leukemic stem cells.
This work facilitates a comprehensive understanding of modern treatment methodology for leukemia. The volume therefore will greatly benefit not only hematologists but also oncologists, all physicians who specialize in blood cancer, and pharmacologists who are involved in the development of therapeutic agents for leukemia.
Editors and Affiliations
About the editor
Takanori Ueda
Vice-President, University of Fukui Faculty of Medical Sciences,
3-9-1 Bunkyo, Fukui 910-8507, Japan
Bibliographic Information
Book Title: Chemotherapy for Leukemia
Book Subtitle: Novel Drugs and Treatment
Editors: Takanori Ueda
DOI: https://doi.org/10.1007/978-981-10-3332-2
Publisher: Springer Singapore
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2017
Hardcover ISBN: 978-981-10-3330-8Published: 26 April 2017
Softcover ISBN: 978-981-10-9844-4Published: 11 September 2018
eBook ISBN: 978-981-10-3332-2Published: 17 April 2017
Edition Number: 1
Number of Pages: VIII, 361
Number of Illustrations: 31 b/w illustrations, 51 illustrations in colour
Topics: Oncology, Hematology
Industry Sectors: Biotechnology, Health & Hospitals, Pharma