MRI Contrast Agents

From Molecules to Particles

  • Sophie Laurent
  • Céline Henoumont
  • Dimitri Stanicki
  • Sébastien Boutry
  • Estelle Lipani
  • Sarah Belaid
  • Robert N. Muller
  • Luce Vander Elst

Part of the SpringerBriefs in Applied Sciences and Technology book series (BRIEFSAPPLSCIENCES)

Also part of the Nanotheranostics book sub series (BRIEFSNANO)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Sophie Laurent, Céline Henoumont, Dimitri Stanicki, Sébastien Boutry, Estelle Lipani, Sarah Belaid et al.
    Pages 1-3
  3. Sophie Laurent, Céline Henoumont, Dimitri Stanicki, Sébastien Boutry, Estelle Lipani, Sarah Belaid et al.
    Pages 5-11
  4. Sophie Laurent, Céline Henoumont, Dimitri Stanicki, Sébastien Boutry, Estelle Lipani, Sarah Belaid et al.
    Pages 13-21
  5. Sophie Laurent, Céline Henoumont, Dimitri Stanicki, Sébastien Boutry, Estelle Lipani, Sarah Belaid et al.
    Pages 23-53
  6. Sophie Laurent, Céline Henoumont, Dimitri Stanicki, Sébastien Boutry, Estelle Lipani, Sarah Belaid et al.
    Pages 55-109
  7. Sophie Laurent, Céline Henoumont, Dimitri Stanicki, Sébastien Boutry, Estelle Lipani, Sarah Belaid et al.
    Pages 111-125

About this book

Introduction

This book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc. 

Keywords

Imaging Probes Iron Oxide Nanoparticles MRI Contrast Agents Nanomaterials in Medicine Nanoparticles in Imaging Nanoparticular Systems Nanotheranostics Paramagnetic Gadolinium Complexes Superparamagnetic Contrast Agents Supramolecular Systems

Authors and affiliations

  • Sophie Laurent
    • 1
  • Céline Henoumont
    • 2
  • Dimitri Stanicki
    • 3
  • Sébastien Boutry
    • 4
  • Estelle Lipani
    • 5
  • Sarah Belaid
    • 6
  • Robert N. Muller
    • 7
  • Luce Vander Elst
    • 8
  1. 1.General, Organic and Biomedical ChemisUniversity of Mons GeneralMonsBelgium
  2. 2.General, Organic and Biomedical ChemistrUniversity of Mons GeneralBelgiumBelgium
  3. 3.General, Organic and Biomedical ChemistrUniversity of Mons GeneralMonsBelgium
  4. 4.Cntr for Microscopy & Molecular Imaginng GosseliesBelgium
  5. 5.General, Organic and Biomedical ChemistrUniversity of Mons General, Organic and Biomedical ChemistrMonsBelgium
  6. 6.General, Organic and Biomedical ChemistrUniversity of Mons GeneralMonsBelgium
  7. 7.General, Organic and Biomedical ChemistrUniversity of Mons GeneralMonsBelgium
  8. 8.General, Organic and Biomedical ChemistrUniversity of Mons General, Organic and Biomedical ChemistrMonsBelgium

Bibliographic information

  • DOI https://doi.org/10.1007/978-981-10-2529-7
  • Copyright Information The Author(s) 2017
  • Publisher Name Springer, Singapore
  • eBook Packages Engineering
  • Print ISBN 978-981-10-2527-3
  • Online ISBN 978-981-10-2529-7
  • Series Print ISSN 2191-530X
  • Series Online ISSN 2191-5318
  • About this book
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