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Molecular Targeted Therapy of Lung Cancer

  • Book
  • © 2017

Overview

Editors:
  1. Yuichi Takiguchi

    1. Department of Medical Oncology Graduate School of Medicine, Chiba University, Chiba, Japan

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  • Discusses the latest molecular targeted therapy of lung cancer including its evaluation and future directions

  • Describes the increasing necessity for new diagnostic technology and strategies for managing various adverse effects and novel methods for evaluating effectiveness and safety

  • Provides a comprehensive overview, which will provide the foundation for new ideas for further advances

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-x
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  2. Diagnosis

    1. Front Matter

      Pages 1-1
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    2. Classification of Adenocarcinoma of the Lung, with a Special Reference to Prognosis

      • Yukio Nakatani, Yoko Yonemori, Jun Matsushima, Takuya Yazawa
      Pages 3-28

    3. Screening Lung Cancer with Low-Dose CT Combined with Molecular Markers

      • Yuichi Takiguchi
      Pages 29-43

    4. PET-CT, Bio-imaging for Predicting Prognosis and Response to Chemotherapy in Patients with Lung Cancer

      • Kyoichi Kaira
      Pages 45-61

    5. Methods in Molecular Diagnosis

      • Koichi Hagiwara
      Pages 63-77

    6. Accurate Nodal Staging and Biomarker Testing with Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration

      • Takahiro Nakajima, Ichiro Yoshino
      Pages 79-96

    7. Next-Generation Sequencing and Bioinformatics

      • Reika Kawabata-Iwakawa, Hidemasa Bono, Masahiko Nishiyama
      Pages 97-115

    8. Companion Diagnostics

      • Emi Noguchi
      Pages 117-136

  3. Treatment

    1. Front Matter

      Pages 137-137
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    2. Small Cell Lung Cancer and Molecular Targeted Therapy

      • Shunichiro Iwasawa
      Pages 139-154

    3. Locally Advanced Non-small Cell Lung Cancer and Targeted Therapy

      • Ikuo Sekine
      Pages 155-165

    4. EGFR Mutant

      • Kunihiko Kobayashi, Hiroshi Kagamu
      Pages 167-189

    5. ALK Mutant

      • Akihiko Gemma
      Pages 191-197

    6. Minor-Driver Mutant

      • Akihiko Miyanaga
      Pages 199-212

    7. Mechanism of Resistance to Targeted Molecular Therapy

      • Masahiro Seike
      Pages 213-225

    8. Immunotherapy

      • Takahiro Ebata
      Pages 227-237

    9. Lung Cancer Complicated with Interstitial Lung Diseases

      • Yuji Minegishi
      Pages 239-252

    10. Management of Adverse Effects by Molecular Targeted Therapy and Immunotherapy

      • Toshimichi Miya
      Pages 253-267

  4. Evaluation

    1. Front Matter

      Pages 269-269
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Keywords

About this book

This book discusses the latest molecular targeted therapy of lung cancer including its evaluation and future directions. It clearly illustrates the initial dramatic effectiveness of molecular targeted therapy, recurrence of the disease, overcoming the wide variety of resistance mechanisms using new-generation molecular targeted agents and potential novel approaches. It also outlines the increasing necessity for new diagnostic technology and strategies for managing different adverse effects and novel methods for evaluating effectiveness and safety. 
Edited and authored by opinion leaders, Molecular Targeted Therapy of Lung Cancer provides a comprehensive overview of the disease and its treatments. It is a valuable resource for graduate students, post-doctoral fellows and faculty staff, as well as researchers involved in clinical and translational research on lung cancer, helping promote new ideas for further advances.

Editors and Affiliations

  • Department of Medical Oncology Graduate School of Medicine, Chiba University, Chiba, Japan

    Yuichi Takiguchi

About the editor

Professor Yuichi TakiguchiDepartment of Medical Oncology, Chiba University Graduate School of Medicine

Bibliographic Information

  • Book Title: Molecular Targeted Therapy of Lung Cancer

  • Editors: Yuichi Takiguchi

  • DOI: https://doi.org/10.1007/978-981-10-2002-5

  • Publisher: Springer Singapore

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media Singapore 2017

  • Hardcover ISBN: 978-981-10-2000-1Published: 06 February 2017

  • Softcover ISBN: 978-981-10-9500-9Published: 15 July 2018

  • eBook ISBN: 978-981-10-2002-5Published: 24 January 2017

  • Edition Number: 1

  • Number of Pages: X, 327

  • Number of Illustrations: 6 b/w illustrations, 48 illustrations in colour

  • Topics: Pneumology/Respiratory System, Oncology, Molecular Medicine

  • Industry Sectors: Biotechnology, Health & Hospitals

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