Molybdenum Cofactors and Their role in the Evolution of Metabolic Pathways

  • Luana Presta
  • Marco Fondi
  • Giovanni Emiliani
  • Renato Fani

Part of the SpringerBriefs in Molecular Science book series (BRIEFSMOLECULAR)

Also part of the SpringerBriefs in Biometals book sub series (SB BIOMETALS)

Table of contents

  1. Front Matter
    Pages i-vi
  2. Luana Presta, Marco Fondi, Giovanni Emiliani, Renato Fani
    Pages 1-3
  3. Luana Presta, Marco Fondi, Giovanni Emiliani, Renato Fani
    Pages 5-19
  4. Luana Presta, Marco Fondi, Giovanni Emiliani, Renato Fani
    Pages 21-31
  5. Luana Presta, Marco Fondi, Giovanni Emiliani, Renato Fani
    Pages 33-52
  6. Luana Presta, Marco Fondi, Giovanni Emiliani, Renato Fani
    Pages 53-66
  7. Luana Presta, Marco Fondi, Giovanni Emiliani, Renato Fani
    Pages 67-75

About this book

Introduction

In this brief, the authors explore and review the current knowledge regarding the role of molybdenum in the evolution of biological systems and their interaction with biogeochemical cycles. Special emphasis is placed on biological nitrogen fixation and the nitrogen element cycle.

The origin and evolution of molybdenum cofactor biosynthetic pathways as well as the evolutionary significance of molybdenum containing enzymes appearance is analyzed.

Original data regarding nitrogen fixation pathways and related enzymes molecular evolution processes is presented.

The trace element molybdenum is essential for nearly all organisms and forms the catalytic center of a large variety of enzymes such as nitrogenase, nitrate reductases, sulphite oxidase and xanthine oxidoreductases.

Keywords

apoenzymes biosynthetic pathways cellular function cofactor insertion evolutionary mechanisms iron–molybdenum cofactors metal activation molybdenum containing cofactors pterin based molybdenum cofactors scaffold formation

Authors and affiliations

  • Luana Presta
    • 1
  • Marco Fondi
    • 2
  • Giovanni Emiliani
    • 3
  • Renato Fani
    • 4
  1. 1.Laboratory of Microbial and Molecular Evolution, Department of BiologyUniversity of FlorenceSesto FiorentinoItaly
  2. 2.Laboratory of Microbial and Molecular Evolution, Department of BiologyUniversity of FlorenceSesto FiorentinoItaly
  3. 3.Trees and Timber Institute National Research Council, IVALSA-CNRTrentoItaly
  4. 4.Laboratory of Microbial and Molecular Evolution, Department of BiologyUniversity of FlorenceSesto FiorentinoItaly

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-017-9972-0
  • Copyright Information The Author(s) 2015
  • Publisher Name Springer, Dordrecht
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-94-017-9971-3
  • Online ISBN 978-94-017-9972-0
  • Series Print ISSN 2191-5407
  • Series Online ISSN 2191-5415
  • About this book
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