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The Essential Guide to N-of-1 Trials in Health

  • Jane Nikles
  • Geoffrey Mitchell

Table of contents

  1. Front Matter
    Pages i-xi
  2. Jane Nikles, Geoffrey Mitchell
    Pages 1-7
  3. Jane Nikles
    Pages 9-17
  4. Robyn L. Tate, Michael Perdices
    Pages 19-41
  5. Geoffrey Mitchell
    Pages 43-55
  6. Geoffrey Mitchell
    Pages 57-66
  7. Keumhee C. Carriere, Yin Li, Geoffrey Mitchell, Hugh Senior
    Pages 67-80
  8. Hugh Senior
    Pages 93-104
  9. Hugh Senior
    Pages 115-123
  10. Andrew Crowden, Gordon Guyatt, Nikola Stepanov, Sunita Vohra
    Pages 125-133
  11. Kerrie Mengersen, James M. McGree, Christopher H. Schmid
    Pages 135-153
  12. Jennifer A. Whitty, Joshua M. Byrnes, Paul A. Scuffham
    Pages 155-174
  13. Margaret Sampson, Larissa Shamseer, Sunita Vohra
    Pages 175-194
  14. Jane Smith, Michael Yelland, Christopher Del Mar
    Pages 195-209
  15. Kerrie Mengersen, James M. McGree, Christopher H. Schmid
    Pages 211-231
  16. Jane Nikles
    Pages 233-241
  17. Back Matter
    Pages 243-245

About this book

Introduction

N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs.  They have the potential to revolutionize the way clinical medicine is practiced.

Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials.

Written and edited by some of the world’s leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more. Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system.

Keywords

Behavioural interventions Clinical decision-making N-of-1 trials Quality Use of Medicines Trial design

Editors and affiliations

  • Jane Nikles
    • 1
  • Geoffrey Mitchell
    • 2
  1. 1.School of MedicineThe University of QueenslandIpswichAustralia
  2. 2.School of MedicineThe University of QueenslandIpswichAustralia

Bibliographic information

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