Zinc Biochemistry, Physiology, and Homeostasis

Recent Insights and Current Trends

  • W.┬áMaret

Table of contents

  1. Front Matter
    Pages i-iv
  2. Eiichi Kimura, Shin Aoki
    Pages 5-18
  3. Carol A. Fierke, Richard B. Thompson
    Pages 19-36
  4. L. Alex Gaither, David J. Eide
    Pages 65-84
  5. Ai Q. Truong-Tran, Joanne Carter, Richard E. Ruffin, Peter D. Zalewski
    Pages 129-144
  6. Christopher J. Frederickson, Ashley I. Bush
    Pages 167-180
  7. Lothar Rink, Philip Gabriel
    Pages 181-197
  8. Kenneth H. Falchuk, Marcelo Montorzi
    Pages 199-209
  9. Back Matter
    Pages 227-236

About this book


Chapters in this book review the remarkable advances in the field of zinc biology over the last decade. Zinc is essential for life, in particular for growth and development, through its role in hundreds of zinc enzymes and thousands of zinc proteins. Its catalytic, structural, and regulatory functions in these proteins impact metabolism, gene expression, and signal transduction, including neurotransmission. Among the micronutrients, zinc may rank with iron as to its importance for public health.

The topics covered range from single molecules to cells and to whole organisms: the chemistry, design, and application of fluorophores for the determination of cellular zinc; the role of zinc in proliferation, differentiation, and apoptosis of cells; proteins that transport, sense, and distribute zinc and together form a cellular homeostatic system; the coordination chemistry of zinc in metalloproteins; the role of zinc in the brain as a neuromodulator/transmitter; the dependence of the immune system on zinc; zinc homeostasis in the whole human body.


Fluor Inorganic Chemistry Nutrition Public Health biochemistry cancer cells enzymes gene expression metabolism physiology proteins tea

Editors and affiliations

  • W.┬áMaret
    • 1
  1. 1.Center for Biochemical and Biophysical Sciences and MedicineHarvard Medical SchoolBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media Dordrecht 2001
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-90-481-5916-1
  • Online ISBN 978-94-017-3728-9
  • Buy this book on publisher's site
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