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Annual Reports in Combinatorial Chemistry and Molecular Diversity

  • W. H. Moos
  • M. R. Pavia

About this book

Introduction

Combinatorial chemistry and molecular diversity approaches to scientific and novel product R & D have exploded in the 1990s. For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research.
The second volume in this series includes contributions on methods, solid phases, purification, analysis, carbohydrates, patent strategies and tactics, diversity profiling and combinatorial series design, and finishes with a survey of chemical libraries yielding biologically active agents and a compendium of solid phase chemistry publications. Each contribution is prepared by a recognized expert resulting in a high quality account of the recent advances in the field.

Keywords

biological carbohydrate carbohydrates chemistry development enzyme mutation pharmaceutical phase purification quality quality control receptor synthesis

Editors and affiliations

  • W. H. Moos
    • 1
  • M. R. Pavia
    • 2
  1. 1.MitokorSan DiegoUSA
  2. 2.Millennium PharmaceuticalsCambridgeUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-017-0735-0
  • Copyright Information Springer Science+Business Media B.V. 1999
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-90-481-5227-8
  • Online ISBN 978-94-017-0735-0
  • Series Print ISSN 1384-2811
  • Buy this book on publisher's site
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Pharma
Chemical Manufacturing
Biotechnology
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