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Immunochemistry in Clinical Laboratory Medicine

Proceedings of a symposium held at the University of Lancaster, March, 1978

  • Conference proceedings
  • © 1979

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Editors:
  1. A. Milford Ward
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  2. J. T. Whicher
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Table of contents (19 papers)

  1. Front Matter

    Pages i-xi
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  2. Methods and Problems in Immunochemistry

    1. Front Matter

      Pages 1-1
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    2. Electrophoresis and Immunoelectrophoresis

      • Pamela G. Riches
      Pages 3-15

    3. Radial immunodiffusion and rocket Immunoelectrophoresis

      • D. Kenny
      Pages 17-22

    4. Automated immunoprecipitation and laser nephelometry

      • P. A. E. White, R. Strong
      Pages 23-33

    5. Antiserum requirements

      • A. C. Munro
      Pages 35-49

    6. Problems encountered in immunochemical technique methodology

      • J. T. Whicher
      Pages 51-61

    7. Specific protein measurement and standardization

      • R. S. Wainwright, J. R. Doggart, D. W. Neill
      Pages 63-73

    8. Quality control

      • D. M. Browning
      Pages 75-81

  3. Specific Proteins in Laboratory Diagnosis

    1. Front Matter

      Pages 83-83
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    2. Structure and function of the immunoglobulins

      • R. S. H. Pumphrey
      Pages 85-97

    3. Immunoglobulins in blood transfusion

      • P. D. J. Holt
      Pages 99-113

    4. Monoclonal proteins

      • J. Kohn
      Pages 115-126

    5. Iron binding proteins

      • A. Jacobs
      Pages 127-133

    6. Albumin

      • Linda Smith
      Pages 135-148

    7. The complement system

      • J. T. Whicher
      Pages 149-163

    8. Alphafetoprotein in obstetrics

      • D. J. H. Brock
      Pages 165-176

    9. Alphafetoprotein in oncology

      • J. Kohn
      Pages 177-182

    10. α1-Antitrypsin

      • A. Milford Ward
      Pages 183-195

    11. Haptoglobin and orosomucoid in lung and breast tumours

      • A. R. Bradwell
      Pages 197-215
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Keywords

About this book

The rapid growth of specific protein estimations in the clinical laboratory over the last 10 years has been due to advances both in methodology and in the understanding of the role of the various plasma proteins in health and disease. This expansion has been made possible by the development of both gel phase and fluid phase techniques for the estimation of proteins and the ready availability of antisera to individual plasma proteins. The specificity of the immunological reaction has allowed the more precise identification and estimation of individual plasma proteins than was possible with dye binding or other chemical techniques, but at the same time these methods have introduced other possible errors and pitfalls. Advances in understanding of the structure and function of various plasma proteins has pointed the way to new clinical applications of plasma protein estimation in the diagnosis and monitoring of disease. The Symposium, of which these are the proceedings, was planned to bring together a number of experts in the field to discuss the available methods and their clinical application.

Bibliographic Information

  • Book Title: Immunochemistry in Clinical Laboratory Medicine

  • Book Subtitle: Proceedings of a symposium held at the University of Lancaster, March, 1978

  • Editors: A. Milford Ward, J. T. Whicher

  • DOI: https://doi.org/10.1007/978-94-011-6591-4

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: MTP Press Limited 1979

  • Softcover ISBN: 978-94-011-6593-8Published: 14 February 2012

  • eBook ISBN: 978-94-011-6591-4Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 247

  • Topics: Medical Biochemistry

  • Industry Sectors: Engineering, Health & Hospitals

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