Advertisement

Inborn Errors of Immunity and Phagocytosis

Monograph based upon Proceedings of the Fifteenth Symposium of The Society for the Study of Inborn Errors of Metabolism

  • F. Güttler
  • J. W. T. Seakins
  • R. A. Harkness

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Defects of Cell-mediated Immunity

    1. Front Matter
      Pages 1-1
    2. R. N. Pahwa, S. G. Pahwa, R. O’Reilly, Elizabeth M. Smithwick, R. A. Good
      Pages 3-68
    3. A. Svejgaard, E. Dickmeiss, G. S. Hansen, P. Platz, L. P. Ryder, M. Thomsen
      Pages 69-85
  3. Enzyme Defects and Immunodeficiency

    1. Front Matter
      Pages 87-87
    2. B. J. M. Zegers, J. W. Stoop, G. F. M. Hendrickx, S. K. Wadman, G. E. J. Staal
      Pages 137-145
    3. S. K. Wadman, P. K. de Bree, G. F. M. Hendrickx, B. J. M. Zegers, J. W. Stoop
      Pages 147-154
    4. B. Björkstén, O. Bäck, B. Hägglöf, A. Tärnvik
      Pages 189-198
  4. Disorders of Non-specific Immunity

    1. Front Matter
      Pages 199-199
    2. D. Romeo, P. Dri, P. Bellavite, F. Rossi
      Pages 231-246
    3. D. Roos, R. S. Weening, J. A. Loos
      Pages 261-286
    4. R. S. Weening, D. Roos, Margriet L. J. van Schaik
      Pages 287-295
    5. R. A. Harkness, M. Grant, S. M. Cockle
      Pages 297-307
    6. S. Olling, R. Hultborn, I. Mattsby-Baltzer
      Pages 315-322
    7. F. Karup Pedersen, K. S. Johansen, J. Rosenkvist, I. Tygstrup, N. H. Valerius
      Pages 349-352
    8. F. Güttler, J. W. T. Seakins, R. A. Harkness
      Pages 353-369
  5. Screening for Immunodeficiency

    1. Front Matter
      Pages 371-371
    2. F. Güttler, J. W. T. Seakins, R. A. Harkness
      Pages 373-386
  6. Back Matter
    Pages 387-391

About this book

Introduction

The rapid growth of immunology has greatly increased our understanding of disease; this growth has also generated a subject which at times appears separated from some of the basic medical sciences. Recent studies in the areas of purine metabolism and of polymorphonuclear neutrophil phago­ cyte function have, however, linked immunology and clinical medicine with biochemistry. The precise defects of the inborn errors of metabolism have now provided good evidence for the importance of purine metabolism specifically the enzymes adenosine deaminase and nucleoside phosphorylase in lymphocyte function. In view of this and the steady advance of clinical and biochemical investigation of the polymorphonuclear neutrophil phago­ cyte, it appeared timely to review the inborn errors of immunity and phagocytosis at the fifteenth annual symposium of the Society for the Study of Inborn Errors of Metabolism at Elsinore, Denmark on September II-14th, I~77. The papers presented at that meeting form the basis of this volume which brings together contributions from immunologists, biochemists and clinicians. This interdisciplinary communication should be helpful to those concerned with immune function in their patients or in the laboratory. The book is divided into four sections, One: defects of cell-mediated immunity, Two: enzyme defects and immunodeficiency, Three: disorders of non-specific immunity and Four: screening for immunodeficiency. Section One contains two reviews, one on immunodeficiency from Robert Good's group in New York and another on the genetics of the immune system from Arne Svejgaard of Copenhagen.

Keywords

growth immune system immunology infection metabolism

Editors and affiliations

  • F. Güttler
    • 1
  • J. W. T. Seakins
    • 2
  • R. A. Harkness
    • 3
  1. 1.John F. Kennedy InstituteGlostrupDenmark
  2. 2.Department of Chemical PathologyInstitute of Child HealthLondon
  3. 3.Division of Perinatal MedicineMRC Clinical Research Centre, HarrowMiddlesexLondon

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-011-6197-8
  • Copyright Information Springer Science+Business Media B.V. 1979
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-011-6199-2
  • Online ISBN 978-94-011-6197-8
  • Buy this book on publisher's site
Industry Sectors
Pharma
Health & Hospitals
Biotechnology
Consumer Packaged Goods