Mutation and Evolution

  • Ronny C. Woodruff
  • James N. ThompsonJr.

Part of the Contemporary Issues in Genetics and Evolution book series (CIGE, volume 7)

Table of contents

  1. Front Matter
    Pages i-2
  2. Deleterious mutations

  3. Neutral (nearly neutral) mutations

  4. Beneficial mutations

  5. Quantitative traits

  6. Mutation, life history, and senescence

    1. Daniel E. L. Promislow, Marc Tatar
      Pages 299-314
    2. C. Martorell, M. A. Toro, C. Gallego
      Pages 315-324
    3. Edward J. Klekowski
      Pages 325-331
  7. Genetic changes

    1. Santiago F. Elena, Lynette Ekunwe, Neerja Hajela, Shenandoah A. Oden, Richard E. Lenski
      Pages 349-358
    2. Malcolm D. Schug, Carolyn M. Hutter, Mohamed A. F. Noor, Charles F. Aquadro
      Pages 359-367
    3. Ling-Wen Zeng, Josep M. Comeron, Bin Chen, Martin Kreitman
      Pages 369-382
  8. Cell lineage selection, germinal mosaics, and evolution

  9. Mutation and the dynamics of adaptation

    1. Daniel L. Hartl, Clifford H. Taubes
      Pages 525-533
    2. Yoshinari Tanaka
      Pages 535-543
    3. Jürgen Tomiuk, Bernt Guldbrandtsen, Volker Loeschcke
      Pages 545-558
    4. Hong-Wen Deng, Yun-Xin Fu, Michael Lynch
      Pages 559-567
    5. Günter P. Wagner, Manfred D. Laubichler, Homayoun Bagheri-Chaichian
      Pages 569-580

About this book


Although debated since the time of Darwin, the evolutionary role of mutation is still controversial. In over 40 chapters from leading authorities in mutation and evolutionary biology, this book takes a new look at both the theoretical and experimental measurement and significance of new mutation. Deleterious, nearly neutral, beneficial, and polygenic mutations are considered in their effects on fitness, life history traits, and the composition of the gene pool. Mutation is a phenomenon that draws attention from many different disciplines. Thus, the extensive reviews of the literature will be valuable both to established researchers and to those just beginning to study this field. Through up-to-date reviews, the authors provide an insightful overview of each topic and then share their newest ideas and explore controversial aspects of mutation and the evolutionary process. From topics like gonadal mosaicism and mutation clusters to adaptive mutagenesis, mutation in cell organelles, and the level and distribution of DNA molecular changes, the foundation is set for continuing the debate about the role of mutation, fitness, and adaptability. It is a debate that will have profound consequences for our understanding of evolution.


Charles Darwin DNA Darwin Mutation evolution evolutionary biology

Editors and affiliations

  • Ronny C. Woodruff
    • 1
  • James N. ThompsonJr.
    • 2
  1. 1.Bowling Green State UniversityBowling GreenUSA
  2. 2.University of OklahomaNormanUSA

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 1998
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-6193-3
  • Online ISBN 978-94-011-5210-5
  • Series Print ISSN 0929-712X
  • Buy this book on publisher's site
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