Animal Cell Technology: Basic & Applied Aspects

1. Fish Cell Biotechnology

   1. Functional Analysis of the Homology and Heterology Promoters in Fish-Cultured Cells

      • T. Aoki, L. Fu, I. Hirono, M. Miyata

      Pages 145-149

2. Novel Bioreactors for Animal Cell Culture

   1. Dialysis Perfusion Systems for the Production and Retention of High-Valued Products from Animal Cells

      • B. Amos, M. Al-Rubeai, A. N. Emery

      Pages 151-156

   2. Methods for Animal Cell Immobilization Using Electrostatic Droplet Generation

      • B. Bugarski, M. F. A. Goosen

      Pages 157-160

   3. Using Oxygen Uptake Rates to Time Infections in the Baculovirus Expression Vector System

      • L. K. Nielsen, T. K. K. Wong, J. Power, S. Reid, P. F. Greenfield

      Pages 161-166

3. Cell Culture Engineering for High Performance Production of Biologicals

   1. On-Line Monitoring and Control of Glucose, Glutamine, Lactate and Ammonium during a High-Cell-Density Cultivation of Hybridoma Cells

      • J. J. Van Der Pol, B. Joksch, U. Spohn, M. Biselli, C. Wandrey

      Pages 167-170

   2. Cultivation of Hybridomas, Human Cancer and Human Primary Cells Using the Miniaturized Hollow Fibre Bioreactor Tecnomouse®

      • U. Marx, W. Merz, S. Koch, A. Nagel, M. Schläfke, P. M. Schlag et al.

      Pages 171-175

   3. Electrically Controlled Production of Monoclonal Antibody by Immobilized Hybridoma

      • M. Aizawa, S. Ishihara, T. Haruyama, E. Kobatake, Y. Ikariyama

      Pages 177-181

   4. Effect of Endogenous Retrovirus Production on Hybridoma Productivity

      • L. Johnson, P. J. Phillips, C. Harbour, J. P. Barford

      Pages 183-190

   5. Effect of Dissolved Oxygen Concentration on Growth and Production of Biomaterials by Animal Cell Culture

      • Jin Wang, Hiroyuki Honda, Yong Soo Park, Shinji Iijima, Takeshi Kobayashi

      Pages 191-195

   6. Enhanced Productivity in Insect Cell Culture by Control of the Chemical Environment

      • K. M. Radford, S. Reid, P. F. Greenfield

      Pages 197-204

   7. Energy Balance and Protein Synthesis in Hybridoma Culture

      • Y. Shirai, A. Kobayashi, M. Yamaguchi, K. Hashimoto

      Pages 205-212

4. Expression of Recombinant Animal Genes in Cultured Cells

   1. Application of Fish Cells Immortalized by Oncogenes — Diagnostic Method for the Detection of Fish Iridovirus (Iridoviridae) by Polymerase Chain Reaction

      • Tadakazu Tamai, Kazunari Tsujimura, Hiroshi Oda, Nobuyuki Sato, Sanetaka Shirahata, Shouji Kimura et al.

      Pages 213-218

   2. Enhancement of Cellular Productivity by Oncogene Transfection

      • Sanetaka Shirahata, Kiichiro Teruya, Takahiro Yano, Junko Watanabe, Hirofumi Tachibana, Hideya Ohashi et al.

      Pages 219-224

   3. Comparison of wild and mutant β-lactoglobulin production between mammalian cells and yeast

      • Y. Katakura, M. Totsuka, A. Ametani, S. Kaminogawa

      Pages 225-229

   4. Enhancement of γ -Carboxylation of Recombinant Activated Protein C by Cell Fusion

      • Yoshiharu Takazawa, Kenji Wakabayashi, Fuminori Miyagi, Hiroyuki Takamatsu, Seiichi Yokoyama

      Pages 231-235

   5. Modulation of oligosaccharide structure of a pro-urokinase derivative (pro-UKΔGS1) by culture conditions

      • Shinji Hosoi, Katsuya Higo, Seiji Sugimoto, Hiromasa Miyaji, Kei Karasawa, Kazuo Yamaguchi et al.

      Pages 237-241

   6. The Analysis of Antigen-Antibody Binding Using Anti-RNase A Single Chain Fv-3A21

      • Eiji Kobayashi, Takahiro Kumamoto, Takeshi Omasa, Kazuhito Fujiyama, Suteaki Shioya, Ken-ichi Suga

      Pages 243-247

   7. Enhanced Transcriptional Activity by Modifying the Chicken Ovalbumin Gene Promoter in the Oviduct Cell of Chickens

      • T. Muramatsu, H. Park, J. Okumura

      Pages 249-253

   8. Expression of a Foreign Gene Introduced Into Bovine Embryos at Early Stages of Development

      • T. Muramatsu, A. Nakamura, J. Okumura

      Pages 255-258

   9. Expression of Milk Protein-Cat Chimeric Genes in Transfected Bovine and Mouse Mammary Epithelial Cells

      • J.-Y. Ahn, K. Yamamoto, N. Aoki, T. Adachi, R. Nakamura, T. Matsuda

      Pages 259-263

Animal cell technology is a growing discipline of cell biology which aims to understand the structure, function and behaviour of differentiated animal cells, and especially the development of such abilities as are useful for industrial purposes. These developments range from clonal expansion of differentiated cells with useful abilities, to optimization of cell culture on industrial scale and modulation of the cells' abilities to produce drugs and monoclonal antibodies.
The sixth volume in this series gives a complete review of today's state of the art in Japan, a country where this field is especially well advanced. It will be of interest to cell biologists, biochemists, molecular biologists, immunologists and other disciplines related to animal cell culture, working in the academic environment as well as in (biotechnology or pharmaceutical) industry.

• Expression
• biotechnology
• cell biology
• development
• protein
• tissue
• transgen
• transgenic animals

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