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The Genetics of Cancer

  • B. A. J. Ponder
  • M. J. Waring

Part of the Cancer Biology and Medicine book series (CABM, volume 4)

Table of contents

  1. Front Matter
    Pages i-ix
  2. D. Eccles, R. Houlston
    Pages 1-19
  3. N. E. Caporaso
    Pages 21-43
  4. J. D. Potter, T. A. Sellers, S. S. Rich
    Pages 45-65
  5. R. A. Eeles
    Pages 67-83
  6. E. T. Stuart, P. Gruss
    Pages 85-97
  7. T. A. Dragani, M. A. Pierotti
    Pages 111-122
  8. M. Hall, P. G. Norris, R. T. Johnson
    Pages 123-157
  9. L. R. Ferguson
    Pages 177-216
  10. Back Matter
    Pages 217-221

About this book

Introduction

It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result.
The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Keywords

biology development genes genetics molecular genetics mutagen prevention prostate cancer

Editors and affiliations

  • B. A. J. Ponder
    • 1
  • M. J. Waring
    • 1
  1. 1.University of CambridgeUK

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-011-0677-1
  • Copyright Information Kluwer Academic Publishers 1995
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-4294-9
  • Online ISBN 978-94-011-0677-1
  • Series Print ISSN 0928-8945
  • Buy this book on publisher's site
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