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The Genetics of Cancer

  • Book
  • © 1995

Overview

Editors:
  1. B. A. J. Ponder

    1. University of Cambridge, UK

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    You can also search for this editor in PubMed   Google Scholar

  2. M. J. Waring

    1. University of Cambridge, UK

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Cancer Biology and Medicine (CABM, volume 4)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-ix
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  2. Breast cancer genetics

    • D. Eccles, R. Houlston
    Pages 1-19

  3. The genetics of lung cancer

    • N. E. Caporaso
    Pages 21-43

  4. Colorectal cancer

    • J. D. Potter, T. A. Sellers, S. S. Rich
    Pages 45-65

  5. The genetics of prostate cancer

    • R. A. Eeles
    Pages 67-83

  6. Lessons from developmental biology

    • E. T. Stuart, P. Gruss
    Pages 85-97

  7. Animal models for the study of genetic susceptibility to cancer

    • M. N. Gould
    Pages 99-110

  8. Animal models to look for polygenic effects in cancer predisposition

    • T. A. Dragani, M. A. Pierotti
    Pages 111-122

  9. Human repair deficiencies and predisposition to cancer

    • M. Hall, P. G. Norris, R. T. Johnson
    Pages 123-157

  10. Implications of studies of inherited predisposition for prevention and treatment

    • C. M. Steel
    Pages 159-175

  11. Mutagenic properties of anticancer drugs

    • L. R. Ferguson
    Pages 177-216

  12. Back Matter

    Pages 217-221
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Keywords

About this book

It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result.
The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Editors and Affiliations

  • University of Cambridge, UK

    B. A. J. Ponder, M. J. Waring

Bibliographic Information

  • Book Title: The Genetics of Cancer

  • Editors: B. A. J. Ponder, M. J. Waring

  • Series Title: Cancer Biology and Medicine

  • DOI: https://doi.org/10.1007/978-94-011-0677-1

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1995

  • Hardcover ISBN: 978-0-7923-8886-9Published: 30 November 1995

  • Softcover ISBN: 978-94-010-4294-9Published: 14 October 2012

  • eBook ISBN: 978-94-011-0677-1Published: 06 December 2012

  • Series ISSN: 0928-8945

  • Edition Number: 1

  • Number of Pages: IX, 221

  • Topics: Oncology, Human Genetics

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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