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Cardiovascular Genetics for Clinicians

  • P. A. Doevendans
  • A. A. M. Wilde

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 239)

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Molecular Genetics in Cardiology

    1. M. M. A. M. Mannens, H. J. M. Smeets
      Pages 1-12
    2. J. P. van Tintelen, C. Marcelis, I. M. van Langen
      Pages 13-28
    3. P. Grossfeld
      Pages 29-34
  3. Atherosclerosis

    1. A. A. Kroon, W. Spiering, P. W. de Leeuw
      Pages 35-49
    2. J. C. Defesche, J. J. P. Kastelein
      Pages 51-58
    3. F. F. Willems, G. H. J. Boers, H. J. Blom
      Pages 59-69
    4. D. Girelli, O. Olivieri, R. Corrocher
      Pages 71-87
    5. J. W. Jukema, W. R. P. Agema
      Pages 89-100
  4. Connective Tissue Disorder

  5. Cardiomyopathy

    1. R. J. E. Jongbloed, B. J. C. van den Bosch, I. F. M. de Coo, H. J. M. Smeets
      Pages 127-137
    2. L. Carrier, R. J. E. Jongbloed, H. J. M. Smeets, P. A. Doevendans
      Pages 139-154
    3. C. Marcelis, P. A. Doevendans, G. Bonne
      Pages 155-167
  6. Arrhythmias

    1. A. A. Wilde
      Pages 169-176
    2. X. H. T. Wehrens, M. A. Vos, A. A. Wilde
      Pages 177-190
    3. R. Brugada, R. Roberts
      Pages 191-198
    4. A. Rampazzo, G. Thiene, C. Basso, A. Nava, G. A. Danieli
      Pages 199-210
  7. Future of Genetics

    1. G. B. van Ommen
      Pages 211-216
  8. Back Matter
    Pages 221-226

About this book

Introduction

All physicians practicing medicine encounter patients suffering from cardiovascular disease. This book has been outlined in such a way that vascular surgeons, general internists, neurologists and cardiologists should be able to use it. The book covers the complete scope of cardiac diseases in addition to chapters on hypertension and atherosclerosis. In many patients there is a family history of cerebrovascular accidents, myocardial infarction or peripheral arterial disease. Also in patients reporting collaps, palpitations and arrhythmias the family is crucial and can provide clues to a genetic cause of the disease. This book is published to guide physicians in the process of determining whether a genetic component is likely to be present. Furthermore, information is provided what the possibilities and limitations of DNA diagnostic techniques are. Finally, the importance of newly identified categories of potential patients, i. e. gene carriers without symptoms or any inducible sign of disease, is highlighted. For some patients a genetic diagnosis is essential to determine appropriate therapy and for counseling? In some other diseases DNA diagnostic tools are available but the relevant for the patients may be less clear. In other families the search for a disease causing gene is ongoing and the possibilities to find genes and to unravel the pathophysiology of the disease is limited by the lack of patients. To give insight into the current state of genetic diagnostics, the authors have classified the cardiovascular diseases.

Keywords

DNA atherosclerosis cardiovascular congenital heart disease diagnostics genetics heart lipoprotein mitochondria pathophysiology physiology protein tissue vascular disease

Editors and affiliations

  • P. A. Doevendans
    • 1
  • A. A. M. Wilde
    • 2
  1. 1.Academic Hospital MaastrichtMaastrichtThe Netherlands
  2. 2.Academic Medical CenterAmsterdamThe Netherlands

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-010-1019-1
  • Copyright Information Kluwer Academic Publishers 2001
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-3888-1
  • Online ISBN 978-94-010-1019-1
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site
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