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Current and Future Immunosuppressive Therapies Following Transplantation

  • Book
  • © 2001

Overview

Editors:
  1. Mohamed H. Sayegh

    1. Harvard Medical School, Boston, USA

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  2. Giuseppe Remuzzi

    1. Mario Negri Institute for Pharmacological Research, Bergamo, Italy

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-ix
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  2. Introduction

    1. Front Matter

      Pages 1-1
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    2. The History of Immunosuppression for Organ Transplantation

      • Johnny C. Hong, Barry D. Kahan
      Pages 3-17

    3. Clinical Trials in Transplant Immunosuppression: What Have We Learned?

      • P. Schnuelle, F. J. van der Woude
      Pages 19-40

  3. Pharmacological Immunosuppression

    1. Front Matter

      Pages 41-41
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    2. Pharmacologic Monitoring of Immunosuppressive Drugs

      • Flavio Gaspari, Norberto Perico, Giuseppe Remuzzi
      Pages 43-59

    3. Use of Corticosteroids in Kidney Transplantion

      • Donald E. Hricik
      Pages 61-84

    4. Mycophenolate Mofetil and Azathioprine

      • John D. Pirsch, Elias David-Neto
      Pages 85-110

    5. Cyclosporine Formulations

      • Venkataraman Ramanathan, J. Harold Helderman
      Pages 111-121

    6. Tacrolimus

      • Ron Shapiro
      Pages 123-142

    7. Sirolimus

      • Barry D. Kahan
      Pages 143-163

    8. New Agents on the Horizon

      • Jochen Klupp, Randall E. Morris
      Pages 165-183

  4. Biologicals

    1. Front Matter

      Pages 185-185
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    2. Why To We Need Induction Therapy?

      • John Vella, John Neylan
      Pages 187-204

    3. Ponyclonal Antilymphocyte Antibodies

      • Paul Morrissey, Anthony P. Monaco
      Pages 205-220

    4. Monoclonal Antibody Targeting of the T Cell Receptor Complex

      • Lucienne Chatenoud
      Pages 221-234

    5. Monoclonal Antibody Targeting of the Il-2R Complex

      • Flavio G. Vincenti
      Pages 235-248

    6. Monoclonal Antibody Targeting of Adhesion Molecules

      • Markus H. Frank, David M. Briscoe
      Pages 249-263

    7. Costimulation Blockade

      • Roy D. Bloom, Laurence A. Turka
      Pages 265-277

    8. Immunomodulatory Function of MHC Peptides

      • Barbara Murphy, Alan Krensky
      Pages 279-292
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Keywords

About this book

This title provides a comprehensive and state-of-the-art summary of current and future immunosuppressive strategies in transplantation, with emphasis on the basic science mechanisms and clinical applicability of these strategies. The uniqueness of this book is the inclusion of up-to-date information on the basic mechanisms of actions of the immunosuppressive drugs as well as a summary of the clinical trials data and the potential use of these drugs in clinical organ transplantation. In addition to describing the various immunosuppressive strategies, the book has three special features, including immunosuppression in xenotransplantation, gene therapy approaches, and transplantation tolerance. A group of outstanding investigators have been assembled to write the chapters. The book is intended for the transplant professional and the specialist who wants to stay abreast of the current status of immunosuppression in organ transplantation. The book is also useful for basic scientists who work in the field of transplantation immunology.

Editors and Affiliations

  • Harvard Medical School, Boston, USA

    Mohamed H. Sayegh

  • Mario Negri Institute for Pharmacological Research, Bergamo, Italy

    Giuseppe Remuzzi

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